| Also known as: |
ANGIOGENIN |
| Other names: |
5, Angiogenin, RNase 5, RNase A family, Ribonuclease 5, angiogenin, angiogenin, epididymis luminal protein 168, ribonuclease, ribonuclease 5, angiogenin |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
ALS9, ANG, HEL168, RNASE4, RNASE5, RNASE5, RNase 5, ANG |
| Gene name synonims: |
ALS9, ANG, HEL168, RNASE4, RNASE5, RNASE5, RNase 5, ANG |
| Other gene names: |
ALS9, ANG, HEL168, RNASE4, RNASE5, RNASE5, RNase 5, ANG |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgM |
| Clone: |
MANG-1 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Angiogenin exerts its vascular stimulation potential through binding to cytoplasmic actin on the surface of endothelial cells, MANG-1 also demonstrates intense staining on carcinoma cells and of endothelial cells in intratumoral vessels, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, a potent angiogenesis inducing polypeptide of approximately 16, also known as ribonuclease 5 demonstrates tRNA specific ribonuclease activity, clone MANG1 stains single cells on human tonsil sections and endothelial cells in human terminal placenta, followed by endocytosis and subsequent translocation to the nucleus Mouse anti Angiogenin, is a monoclonal antibody specific for angiogenin, this in turn is regulated by binding to the ribonuclease inhibitor, /strong>, 5kDa responsible for inducing vascularization in both normal and malignant tissues through activation of vascular endothelium and smooth muscle cells ant triggering a number of processes including Cell migration and proliferation (Reviewed in) Angiogenin, ANGIOGENIN <, Mouse anti Human Angiogenin (MANG-1)<, strong> |
| Form/Appearance: |
S/N (Tissue Culture Supernatant - lyophilised) |
| Concentration: |
3 mg/ml, IgG concentration 0 |
| Storage and shipping: |
After reconstitution Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term, Shelf Life: 12 months from date of reconstitution, Temperature variations in the range between +1C to +7C are tolerable, Prior to reconstitution Keep the antibody refrigerated at +4 degrees Celsius, Storage in frost-free freezers is not recommended |
| Tested applications:: |
Immunohistology - Frozen (IHC), Immunohistology - Paraffin (IHC), ELISA (EIA) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
ANGIOGENIN |
| Short name: |
MOUSE Anti-HUMAN ANGIOGENIN Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens ANGIOGENIN (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
483 |
| Gene: |
ANG |
More about : ANG |
| Long gene name: |
angiogenin |
| Synonyms gene name: |
5 , RNase A family, angiogenin, ribonuclease |
| Synonyms: |
RNASE5 RAA1 |
| Synonyms name: |
ribonuclease A family member 5 |
| Locus: |
14q11, 2 |
| Discovery year: |
1989-05-23 |
| Entrez gene record: |
283 |
| Pubmed identfication: |
1978563 |
| RefSeq identity: |
NM_001097577 |
| Classification: |
Ribonuclease A family |
| Havana BLAST/BLAT: |
OTTHUMG00000029576 |
| Locus Specific Databases: |
ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database LRG_653 |