| Also known as: |
CD18 |
| Other names: |
CD18/11B, CD18/11C, Cell surface adhesion glycoproteins LFA-1/CR3/p150, Complement receptor C3 subunit beta, Integrin beta-2, beta 2, beta 2 (complement component 3 receptor 3 and 4 subunit), cell surface adhesion glycoprotein LFA-1/CR3/P150, cell surface adhesion glycoproteins LFA-1/CR3/p150, complement receptor C3 beta-subunit, complement receptor C3 subunit beta, integrin, integrin beta chain, integrin beta-2, leukocyte cell adhesion molecule CD18, leukocyte-associated antigens CD18/11A, 95 subunit beta, 95 subunit beta, 959 beta subunit precursor), integrin beta-2 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD18 |
| Other gene names: |
CD18, CD18, ITGB2, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7, MFI7, ITGB2 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2b |
| Clone: |
3, YFC118 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The CD18 antigen is an integral membrane glycoprotein of 95kD molecular weight - known as the b chain, The CD18 antigen is non-covalently linked to CD11a, The CD18 molecule is the receptor for ICAM-1 and is thus important for cell adhesion, The main cellular reactivity of antibody YFC 118, This particular antibody might cross react with speacies outside of the listed ones, YFC118, b, c molecules, of the LFA-1 complex, 3 blocks homotypic adhesion and other lymphocyte functions which involve the LFA-1 antigen, 3 is a strong reactivity with Leucocytes (platelets negative), 3 was clustered at the Fourth International Workshop on Leucocyte Differentiation Antigen (code number N221) as recognising the CD18 antigen, CD18 YFC118 |
| Form/Appearance: |
Phycoerythrin (RPE) - lyophilised), RPE (Purified IgG conjugated to R |
| Storage and shipping: |
DO NOT FREEZE, Following reconstitution Keep the antibody refrigerated at +4 degrees Celsius, If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Shelf Life: 18 months from date of reconstitution, Temperature variations in the range between +1C to +7C are tolerable, Temperature variations in the range between +1C to +7C are tolerable, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Prior to reconstitution Keep the antibody refrigerated at +4 degrees Celsius |
| Tested applications:: |
Flow Cytometry (FACS) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD18:RPE |
| Short name: |
RAT ANTI HUMAN CD18:RPE Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens CD18:RPE (Antibody to), RAT antibody to H |
| Alternative technique: |
antibodies |
| Identity: |
6155 |
| Gene: |
ITGB2 |
More about : ITGB2 |
| Long gene name: |
integrin subunit beta 2 |
| Synonyms gene: |
CD18 MFI7 |
| Synonyms gene name: |
beta 2 (antigen CD18 (p95), beta 2 (complement component 3 receptor 3 and 4 subunit) , integrin, lymphocyte function-associated antigen 1, macrophage antigen 1 (mac-1) beta subunit) integrin |
| Synonyms: |
LFA-1 MAC-1 |
| Synonyms name: |
complement component 3 receptor 3 and 4 subunit |
| Locus: |
21q22, 3 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
AK222505 |
| Entrez gene record: |
3689 |
| RefSeq identity: |
NM_000211 |
| Classification: |
Complement system Integrin beta subunits CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000090257 |
| Locus Specific Databases: |
ITGB2base: Mutation registry for Leukocyte adhesion deficiency I (LAD-I) LRG_76 |