MOUSE Anti-CHLAMYDIA LPS Antibody

Catalog number:	GENTAUR-58bde0c5ea025 Buy Now
Price:	993 €
Supplier:	acr
Product name:	MOUSE Anti-CHLAMYDIA LPS Antibody
Quantity:	1 mg
Other quantities:	1000ug 437€ 500ug 304€
Related search:	lps lipid antibody mammalian species immunostimulatory antibodies signaling specific identified

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Also known as:	CHLAMYDIA LPS
Category:	Antibodies
Subcategory:	Mnoclonal antibodies
Clonality:	Monoclonal
Immunoglobulin isotype:	IgG2b
Clone:	NYRChlam LPS
Host organism:	Mouse (Mus musculus)
Species reactivity:	Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Bacterial
Specificity and cross-reactivity:	LPS is a common feature of the outer envelope of gram negative bacteria, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, Studies have shown however, This antibody has not been cross-adsorbed and may react with LPS from related species, This particular antibody might cross react with speacies outside of the listed ones, does evoke an immune response, it displays only weak endotoxic activity when compared to that of other bacteria such as <, lipopolysaccharide (LPS), or <, that whilst the LPS of <, triggering an innate immune response, which acts as a potent endotoxin, /i>, /i>, /i>, /i>, CHLAMYDIA LPS This item is specific for <, Chlamydia trachomatis<, Chlamydia<, Neisseria gonorrhoeae<, Salmonella minnesota<, i>, i>, i>, i>
Form/Appearance:	Purified (Purified IgG - lyophilised)
Concentration:	0 mg/ml after reconstitution, IgG concentration 1
Storage and shipping:	After reconstitution For optimal long term storage, If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 12 months from date of reconstitution, Storage in frost-free freezers is not recommended, Temperature variations in the range between +1C to +7C are tolerable, the antibody should be kept at -20 degrees Celsius, the antibody should be stored undiluted, Prior to reconstitution Keep the antibody refrigerated at +4 degrees Celsius
Tested applications::	ELISA (EIA)
Properties:	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene:	According to the current model, Agonistic forms of LPS or lipid A trigger numerous physiological immunostimulatory effects in mammalian organisms, Cells of the myeloid lineage have been shown to be the primary cellular sensors for LPS in the mammalian immune system, During the past decade, In addition, LPS consist of a poly- or oligosaccharide region that is anchored in the outer bacterial membrane by a specific carbohydrate lipid moiety termed lipid A, Some members of the latter more heterogeneous group are capable of antagonizing the effects of strongly stimulatory LPS/lipid A forms, The elucidation of structure-activity correlations in LPS and lipid A has not only contributed to a molecular understanding of both immunostimulatory and toxic septic processes, The lipid A component is the primary immunostimulatory center of LPS, With respect to immunoactivation in mammalian systems, but has also re-animated the development of new pharmacological and immuno-stimulatory strategies for the prevention and therapy of infectious and malignant diseases, but--in higher doses--can also lead to pathological reactions such as the induction of septic shock, enormous progress has been obtained in the elucidation of the central LPS/lipid A recognition and signaling system in mammalian phagocytes, leading to the rapid activation of an intracellular signaling network that is highly homologous to the signaling systems of IL-1 and IL-18, several natural or derivative lipid A structures have been identified that display comparatively low or even no immunostimulation for a given mammalian species, the classical group of strongly agonistic (highly endotoxin) forms of LPS has been shown to be comprised of a rather similar set of lipid A types, the membrane-bound or soluble forms of CD14 and the newly identified Toll-like receptor 4 (TLR4)*MD-2 complex, the specific cellular recognition of agonistic LPS/lipid A is initialized by the combined extracellular actions of LPS binding protein (LBP), Bacterial pathogen lipopolysaccharides (LPS) are the major outer surface membrane components present in almost all Gram-negative bacteria and act as extremely strong stimulators of innate or natural immunity in diverse eukaryotic species ranging from insects to humans | More about : According to the current model, Agonistic forms of LPS or lipid A trigger numerous physiological immunostimulatory effects in mammalian organisms, Cells of the myeloid lineage have been shown to be the primary cellular sensors for LPS in the mammalian immune system, During the past decade, In addition, LPS consist of a poly- or oligosaccharide region that is anchored in the outer bacterial membrane by a specific carbohydrate lipid moiety termed lipid A, Some members of the latter more heterogeneous group are capable of antagonizing the effects of strongly stimulatory LPS/lipid A forms, The elucidation of structure-activity correlations in LPS and lipid A has not only contributed to a molecular understanding of both immunostimulatory and toxic septic processes, The lipid A component is the primary immunostimulatory center of LPS, With respect to immunoactivation in mammalian systems, but has also re-animated the development of new pharmacological and immuno-stimulatory strategies for the prevention and therapy of infectious and malignant diseases, but--in higher doses--can also lead to pathological reactions such as the induction of septic shock, enormous progress has been obtained in the elucidation of the central LPS/lipid A recognition and signaling system in mammalian phagocytes, leading to the rapid activation of an intracellular signaling network that is highly homologous to the signaling systems of IL-1 and IL-18, several natural or derivative lipid A structures have been identified that display comparatively low or even no immunostimulation for a given mammalian species, the classical group of strongly agonistic (highly endotoxin) forms of LPS has been shown to be comprised of a rather similar set of lipid A types, the membrane-bound or soluble forms of CD14 and the newly identified Toll-like receptor 4 (TLR4)*MD-2 complex, the specific cellular recognition of agonistic LPS/lipid A is initialized by the combined extracellular actions of LPS binding protein (LBP), Bacterial pathogen lipopolysaccharides (LPS) are the major outer surface membrane components present in almost all Gram-negative bacteria and act as extremely strong stimulators of innate or natural immunity in diverse eukaryotic species ranging from insects to humans
Gene target:	CHLAMYDIA LPS
Short name:	MOUSE Anti-CHLAMYDIA LPS Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Alternative name:	MOUSE antibody to-CHLAMYDIA LPS (Antibody to)
Alternative technique:	antibodies

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• #lipid
• #antibody
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• #immunostimulatory
• #antibodies
• #signaling
• #specific
• #identified