| Also known as: |
CD61 |
| Other names: |
Integrin beta-3, Platelet membrane glycoprotein IIIa, antigen CD61), beta 3 (platelet glycoprotein IIIa, integrin, integrin beta-3, platelet membrane glycoprotein IIIa, integrin beta-3 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD61 |
| Other gene names: |
BDPLT2, CD61, GP3A, GP3A, GPIIIa, GPIIIa, GT, ITGB3, ITGB3 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
PM6/13 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
, CD61 is a receptor for fibrinogen, CD61 is expressed on platelets and megakaryocytes in association with CD41, Clone PM6/13 has been reported to inhibit binding of fibronectin to activated human platelets, In functional studies it can be used to inhibit agonist induced platelet aggregation, Removal of Sodium Azide is recommended prior to use in functional assays, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This molecule associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) at the cell surface, This particular antibody might cross react with speacies outside of the listed ones, and on endothelial cells, fibronectin, monocytes, platelets and osteoclasts in association with CD51, vWF, vitronectin and thrombospondin, which is the integrin beta 3 chain, CD61 This item recognises a 105kD glycoprotein |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
IgG concentration 1 miligram per 1 mililiter |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blot (WB), Immunohistology - Frozen (IHC) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD61 |
| Short name: |
MOUSE Anti-HUMAN CD61 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens CD61 (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
6156 |
| Gene: |
ITGB3 |
More about : ITGB3 |
| Long gene name: |
integrin subunit beta 3 |
| Synonyms gene: |
GP3A |
| Synonyms gene name: |
antigen CD61) , beta 3 (platelet glycoprotein IIIa, integrin |
| Synonyms: |
CD61 GPIIIa |
| Synonyms name: |
platelet glycoprotein IIIa antigen CD61 |
| Locus: |
17q21, 32 |
| Discovery year: |
1988-06-09 |
| Entrez gene record: |
3690 |
| Pubmed identfication: |
2454952 |
| RefSeq identity: |
NM_000212 |
| Classification: |
Integrin beta subunits CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000171956 |
| Locus Specific Databases: |
LRG_481 |