| known also as: |
Anti-RABBIT ANTI VPS34 |
| known also as: |
RABBIT ANTI VPS34 |
| known also as: |
Lapin ANTI VPS34 |
| known also as: |
VPS34 |
| Other names: |
PI3-kinase type 3, PI3K type 3, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphoinositide-3-kinase class 3, class 3, phosphatidylinositol 3-kinase catalytic subunit type 3, phosphoinositide-3-kinase, ptdIns-3-kinase type 3, phosphatidylinositol 3-kinase catalytic subunit type 3 |
| Gene name: |
VPS34 |
| Other gene names: |
5330434F23Rik, PI3-kinase type 3, PI3K type 3, Pik3c3, Vps34, Pik3c3 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
Bif-1, Distinct complexes of VPS34 have been shown to regulate endocytic processes vital for late-stage autophagosome-lysosome fusion, _x000D_This item has been tested in immunofluorescence using HUVEC cells, _x000D_VPS34 plays a role in the transport of lysosomal enzyme precursors to lysosomes, a ubiquitously expressed class III PI3K (phosphoinositide 3-kinase), and UVRAG, and functions as the catalytic subunit of the PI3K complex, and has been strongly implicated as a regulator of autophagy, and in endocytosis and vesicular trafficking, and member of the PI3/PI4-kinase family, forming a multi-protein complex with the proautophagic tumor suppressors Beclin1/Atg6, in conjunction with Hoescht 33342 (blue) nuclear staining, in the initiation of autophagosome formation, otherwise known as PI3-kinase type 3 (PIK3C3), which specifically utilizes phosphatidylinositol (PtdIn) as a substrate, VPS34 This item specifically recognises VPS34 (vacuolar protein sorting 34), _x000D_ |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Immunofluorescence (IF), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
VPS34 |
| Short name: |
Anti-VPS34 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
antibody to-VPS34 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8974 |
| Gene: |
PIK3C3 |
More about : PIK3C3 |
| Long gene name: |
phosphatidylinositol 3-kinase catalytic subunit type 3 |
| Synonyms gene name: |
catalytic subunit type 3 , class 3 phosphatidylinositol 3-kinase, phosphoinositide-3-kinase |
| Synonyms: |
Vps34 |
| Locus: |
18q12, 3 |
| Discovery year: |
1998-05-21 |
| GenBank acession: |
Z46973 |
| Entrez gene record: |
5289 |
| Pubmed identfication: |
7628435 |
| RefSeq identity: |
NM_002647 |
| Classification: |
Phosphatidylinositol 3-kinase subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000132593 |