| Also known as: |
C4d |
| Other names: |
Basic complement C4, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3, Chido form of C4, Complement C4-B, basic complement C4, complement C4-B, complement C4B1a, complement component 4B (Chido blood group), complement C4-B preproprotein |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
C4d |
| Other gene names: |
C4B, C4B1, C4B12, C4B2, C4B3, C4B5, C4BD, C4F, CH, CO4, CO4, CPAMD3, CPAMD3, C4B |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
057-51, 1, 5, 6 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
C4b levels are strictly regulated, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, Single site cleavage of the C4b's alpha chain by Factor I forms iC4b and blocks C3 convertase, The complement 1 complex cleaves complement 4 (C4) to form C4b and C4a, The short half life of C4d means that it is present in serum at high enough concentrations to make it a useful marker for classical complement activation, This particular antibody might cross react with speacies outside of the listed ones, This requires C4 binding protein or CR1 as a cofactor, _x000D__x000D_C4 has been linked to susceptibility to systemic lupus erythematosous, iC4b is further degraded into C4d and C4c, inhibiting opsonisation and activation of the classical pathway, C4d This item recognises a neoantigen on the secreted protein complement component 4d (C4d) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Flow Cytometry (FACS), Immunohistology - Frozen (IHC), ELISA (EIA) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
C4d (NEOANTIGEN) |
| Short name: |
MOUSE Anti-HUMAN C4d (NEOANTIGEN) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens C4d (NEOANTIGEN) (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |