| Also known as: |
CLUSTERIN |
| Other names: |
Aging-associated gene 4 protein, Alternative name(s):, Alternative name(s):, Apo-J, ApoJalpha, ApoJbeta, Apolipoprotein J, CLI, Clusterin, Complement cytolysis inhibitor, Complement cytolysis inhibitor a chainClusterin alpha chain, Complement cytolysis inhibitor b chain, Complement-associated protein SP-40, Ku70-binding protein 1, NA1/NA2, TRPM-2Cleaved into the following 2 chains:Clusterin beta chain, Testosterone-repressed prostate message 2, aging-associated protein 4, apolipoprotein J, clusterin, clusterin, complement cytolysis inhibitor, complement lysis inhibitor, complement-associated protein SP-40, ku70-binding protein 1, sulfated glycoprotein 2, testosterone-repressed prostate message 2, 40, 40, clusterin preproprotein |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
AAG4, APO-J, APOJ, APOJ, Apo-J, CLI, CLI, CLI, CLU, CLU1, CLU2, KUB1, KUB1, NA1/NA2, SGP-2, SGP2, SP-40, TRPM-2, TRPM-2, TRPM2, CLU |
| Gene name synonims: |
AAG4, APO-J, APOJ, APOJ, Apo-J, CLI, CLI, CLI, CLU, CLU1, CLU2, KUB1, KUB1, NA1/NA2, SGP-2, SGP2, SP-40, TRPM-2, TRPM-2, TRPM2, CLU |
| Other gene names: |
AAG4, APO-J, APOJ, APOJ, Apo-J, CLI, CLI, CLI, CLU, CLU1, CLU2, KUB1, KUB1, NA1/NA2, SGP-2, SGP2, SP-40, TRPM-2, TRPM-2, TRPM2, CLU |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
3R3/2 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Clusterin acts as an extracellular chaperone inhibiting the formation of human lysozyme amyloid associated with Alzheimer's disease, Clusterin is also important in spermatogenesis and is secreted by Sertoli cells, Clusterin is overexpressed in human prostate cancer, Clusterin suppression can sensitise cells to chemotherapy, It exists in two forms, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The secreted form is thought to inhibit apoptotic signalling by BAX, This particular antibody might cross react with speacies outside of the listed ones, _x000D_Part of the SC5b-9 complex, a pro-apoptotic form localised to the nucleus and a pro-survival secreted form, alpha and beta, an ubiquitously expressed protein of two 40-kD chains, breast cancers and squamous cell carcinomas, clusterin prevents the binding of a C5b-C7 complex to the membrane of the target cell inhibiting the complement cascade, covalently joined by disulfide bonds, CLUSTERIN This item recognises clusterin, _x000D_Both are thought to be involved in DNA repair and cell cycle regulation |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
ELISA (EIA), Flow Cytometry (FACS), Immunohistology - Frozen (IHC), Western Blot (WB) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CLUSTERIN |
| Short name: |
MOUSE Anti-HUMAN CLUSTERIN Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens CLUSTERIN (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
2096 |
| Gene: |
CLUL1 |
More about : CLUL1 |
| Long gene name: |
clusterin like 1 |
| Synonyms gene name: |
clusterin-like 1 (retinal) |
| Synonyms name: |
retinal clusterin-like protein |
| Locus: |
18p11, 32 |
| Discovery year: |
2000-05-30 |
| GenBank acession: |
D63813 |
| Entrez gene record: |
27098 |
| Pubmed identfication: |
10675623 14507903 |
| Havana BLAST/BLAT: |
OTTHUMG00000178252 |