| Also known as: |
EPSTEIN-BARR VIRUS LMP2A |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
14B7 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Viral |
| Specificity and cross-reactivity: |
EBV is a human herpesvirus, Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B, LMP2A forms aggregates in the plasma membranes of B lymphocytes, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_Clone 14B7 detects wild-type LMP2A protein, _x000D__x000D_EBV latently infects B lymphocytes, _x000D__x000D_Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells <, and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents, <, <, /I>, /u>, EPSTEIN-BARR VIRUS LMP2A This item recognises latent membrane protein 2A (LMP2A) of Epstein-Barr virus (EBV), I>, in vitro<, u> |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
EPSTEIN-BARR VIRUS LMP2A |
| Short name: |
RAT ANTI EPSTEIN-BARR VIRUS LMP2A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RAT antibody to EPSTEIN-BARR VIRUS LMP2A (Antibody to) |
| Alternative technique: |
antibodies |