| Also known as: |
CD244 |
| Other names: |
CD244 molecule, NAIL, NK cell activation inducing ligand NAIL, NK cell activation-inducing ligand, NK cell activation-inducing ligand, NK cell type I receptor protein 2B4, NK cell type I receptor protein 2B4, NKR2B4, Natural killer cell receptor 2B4, SLAM family member 4, SLAMF4, Signaling lymphocytic activation molecule 4, h2B4, h2B4, natural killer cell receptor 2B4, natural killer cell receptor 2B4, natural killer cell receptor 2B4 isoform 2 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD244 |
| Other gene names: |
2B4, 2B4, CD244, NAIL, NAIL, NKR2B4, NKR2B4, Nmrk, SLAMF4, SLAMF4, h2B4, CD244 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
2B4, 69 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
CD14+ monocytes, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The ligand of 2B4 is CD48, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_CD244 was originally identified as an activating receptor on NK cells, _x000D__x000D_The glycoprotein CD244 is a member of the SLAM family of receptors which is expressed on natural killer (NK) cells, a GPI-anchored membrane protein also belonging to the SLAM family, also known as natural killer receptor 2B4 (NKG2B4), although recent studies suggest that the receptor may have a wide range of activities including NK cell activation, and a subset of CD8+ T cells, costimulation, depending on the cell type and stage of differentiation, gamma delta T cells, or even inhibition, CD244 This item is specific for the CD244 cell surface antigen |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Flow Cytometry (FACS), Immunoprecipitation (IP) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD244 |
| Short name: |
MOUSE Anti-HUMAN CD244 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
natural killer cellular receptor 2B4 (Antibody to), sapiens CD244 molecule, MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD244 and IDBG-104114 and ENSG00000122223 and 51744, CD244 and IDBG-630400 and ENSBTAG00000002951 and 513468, Cd244 and IDBG-204694 and ENSMUSG00000004709 and 18106, Cell surfaces, natural killer cell receptor 2B4, protein binding, this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0007165 and signal transduction and biological process this GO :0007596 and blood coagulation and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0050900 and leukocyte migration and biological process, this GO :0004872 : receptor activity, this GO :0004872 : receptor activity and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, CD244 molecule |
| Identity: |
18171 |
| Gene: |
CD244 |
More about : CD244 |
| Long gene name: |
CD244 molecule |
| Synonyms gene name: |
natural killer cell receptor 2B4 , natural killer cell receptor 2B4 CD244 natural killer cell receptor 2B4 CD244 molecule |
| Synonyms: |
2B4 NAIL NKR2B4 Nmrk SLAMF4 |
| Locus: |
1q23, 3 |
| Discovery year: |
2003-10-23 |
| GenBank acession: |
AF105261 |
| Entrez gene record: |
51744 |
| Pubmed identfication: |
3772297 10458320 |
| RefSeq identity: |
NM_016382 |
| Classification: |
Immunoglobulin like domain containing CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000028606 |