| known also as: |
Anti-GOAT ANTI HUMAN AMPK ALPHA 2 |
| known also as: |
Caprine ANTI HUMAN AMPK ALPHA 2 |
| known also as: |
Caprinae ANTI Homo sapiens AMPK ALPHA 2 |
| known also as: |
AMPK ALPHA 2 |
| Other names: |
5'-AMP-activated protein kinase, 5'-AMP-activated protein kinase catalytic subunit alpha-2, 5'-AMP-activated protein kinase catalytic subunit alpha-2, ACACA kinase, ACACA kinase, AMP-activated, AMPK subunit alpha-2, AMPK-alpha-2 chain, Acetyl-CoA carboxylase kinase (EC:2, HMGCR kinase, HMGCR kinase, Hydroxymethylglutaryl-CoA reductase kinase (EC:2, acetyl-CoA carboxylase kinase, alpha 2 catalytic subunit, catalytic alpha-2 chain, hydroxymethylglutaryl-CoA reductase kinase, protein kinase, 27), 31), 5'-AMP-activated protein kinase catalytic subunit alpha-2, 7, 7, 11, 11 |
| Gene name: |
AMPK ALPHA 2 |
| Other gene names: |
ACACA kinase, AMPK, AMPK, AMPK subunit alpha-2, AMPK2, AMPK2, AMPKa2, HMGCR kinase, PRKAA, PRKAA2, PRKAA2 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Goat |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
_x000D__x000D_AMPK has been implicated as a suppressor of cell proliferation of both normal and malignant cells, a Serine/threonine-protein kinase and the catalytic subunit of the AMP-activated protein kinase (AMPK), a central metabolic sensor, and recent studies have shown that the binding of AMPK to the PS domain of ULK1, and that the phosphorylation of raptor by AMPK, essential for the regulation of fatty acid and cholesterol synthesis, in response to fluctuations in nutrient and intracellular energy levels, is essential for ULK1-mediated autophagy, otherwise known as PRKAA2, plays an important role in autophagy induction, AMPK ALPHA 2 This item specifically recognises AMPK alpha 2, _x000D__x000D_ |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
IgG concentration 500ug/1000ul |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
AMPK ALPHA 2 |
| Short name: |
GOAT ANTI HUMAN AMPK ALPHA 2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens AMPK a 2 (Antibody to), caprine antibody to H |
| Alternative technique: |
antibodies |
| Identity: |
9377 |
| Gene: |
PRKAA2 |
More about : PRKAA2 |
| Long gene name: |
protein kinase AMP-activated catalytic subunit alpha 2 |
| Synonyms gene: |
PRKAA |
| Synonyms gene name: |
AMP-activated, alpha 2 catalytic subunit , protein kinase |
| Synonyms: |
AMPK AMPKa2 |
| Locus: |
1p32, 2 |
| Discovery year: |
1995-12-12 |
| GenBank acession: |
BC069823 |
| Entrez gene record: |
5563 |
| Pubmed identfication: |
7959015 |
| RefSeq identity: |
NM_006252 |
| Havana BLAST/BLAT: |
OTTHUMG00000008282 |