| Also known as: |
CD104 |
| Other names: |
Integrin beta-4, N/A, integrin beta 4, integrin beta-4, Integrin beta-4 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD104 |
| Other gene names: |
AA407042, C230078O20, CD104, Itgb4, N/A, Itgb4 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
346-11A |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
CD104 is also expressed on peripheral neurones, In mice, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_Expression of CD104 is localised to the basal region of a wide variety of epithelial cells, _x000D__x000D_Studies suggest that the CD49f/CD104 integrin is involved in cell matrix adhesion but expression of the CD49f/CD104 integrin in endothelial cells is thought to have a different function, _x000D__x000D_The alpha 6 beta 4 (CD49f/CD104) integrin has been identified as a component of hemidesmosomes in stratified squamous epithelium where it plays an important role in the adhesion of epithelia to basement membrane, a 200kD glycoprotein that can associate with integrin alpha 6 (CD49f) to form a heterodimer on the cell surface, carcinoma cell lines and a subset of endothelial cells, CD104 This item recognises mouse integrin beta 4 (CD104) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Flow Cytometry (FACS), Immunohistology - Frozen (IHC), Immunoprecipitation (IP), Western Blot (WB) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD104 |
| Short name: |
RAT ANTI MOUSE CD104 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RAT antibody to MOUSE CD104 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6158 |
| Gene: |
ITGB4 |
More about : ITGB4 |
| Long gene name: |
integrin subunit beta 4 |
| Synonyms gene name: |
beta 4 , integrin |
| Synonyms: |
CD104 |
| Locus: |
17q25, 1 |
| Discovery year: |
1991-08-06 |
| Entrez gene record: |
3691 |
| Pubmed identfication: |
2070796 |
| Classification: |
Integrin beta subunits CD molecules Fibronectin type III domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000179814 |