| Also known as: |
CD121a |
| Other names: |
CD121 antigen-like family member A, CD121 antigen-like family member A, IL-1 receptor alpha chain, IL-1R-1, IL-1R-alpha, IL-1R-alpha, IL-1RT-1, IL-1RT1, Interleukin-1 receptor alpha, Interleukin-1 receptor type 1, Interleukin-1 receptor type I, interleukin 1 receptor, interleukin-1 receptor alpha, interleukin-1 receptor type 1, interleukin-1 receptor type I, p80, p80, type I, interleukin-1 receptor type 1 isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD121a |
| Other gene names: |
CD121a, CD121b, IL-1R-1, IL-1R-alpha, IL-1RT-1, IL-1RT1, IL-iR, Il-1r1, Il1r-1, Il1r1, Il1ra, mIL-1R1, mIL-1RI, sIL-1R1, sIL-1RI, Il1r1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
JAMA-147 |
| Host organism: |
Hamster |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
CD121a is weakly expressed on most cells and tissues including T lymphocytes, Clone JAMA-147 has been reported to block IL-1 dependent cellular responses, IL-1 alpha, IL-1 beta and IL-1 receptor antagonist, IL-1 is a mediator of inflammation and can elicit a variety of other biological responses through binding to CD121a, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The ligands for CD121a are the interleukin-1 (IL-1) family members, This particular antibody might cross react with speacies outside of the listed ones, epithelial cells and dendritic cells, thymocytes, which is the 80kD type I interleukin-1 receptor, with stronger expression reported on fibroblasts, CD121a This item recognises murine CD121a |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Immunoprecipitation (IP), Flow Cytometry (FACS) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD121a |
| Short name: |
HAMSTER ANTI MOUSE CD121a Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
HAMSTER antibody to MOUSE CD121a (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
5993 |
| Gene: |
IL1R1 |
More about : IL1R1 |
| Long gene name: |
interleukin 1 receptor type 1 |
| Synonyms gene: |
IL1R IL1RA |
| Synonyms gene name: |
interleukin 1 receptor, type I |
| Synonyms: |
D2S1473 CD121A |
| Synonyms name: |
interleukin-1 receptor, type I |
| Locus: |
2q11, 1 , 2-q12 |
| Discovery year: |
1990-06-27 |
| GenBank acession: |
M27492 |
| Entrez gene record: |
3554 |
| Pubmed identfication: |
1833184 10191101 |
| Classification: |
I-set domain containing CD molecules Immunoglobulin like domain containing Interleukin receptors TIR domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000130783 |