| Also known as: |
CD195 |
| Other names: |
C-C chemokine receptor type 5, C-C chemokine receptor type 5, C-C motif chemokine receptor 5 A159A, CHEMR13, HIV-1 fusion coreceptor, HIV-1 fusion coreceptor, chemokine (C-C motif) receptor 5 (gene/pseudogene), chemokine receptor CCR5, chemr13, C-C chemokine receptor type 5 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD195 |
| Other gene names: |
C-C CKR-5, CC-CKR-5, CC-CKR-5, CCCKR5, CCR-5, CCR-5, CCR5, CCR5, CD195, CKR-5, CKR5, CMKBR5, CMKBR5, IDDM22, CCR5 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
E11/19 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
CD195 is expressed by a subset of T lymphocytes and by monocytes, CD195 is rapidly phosphorylated within the C-terminal domain, It plays a key role in regulating the activation and migration of leukocytes, Recent studies have shown that upon ligand stimulation, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This antibody has been demonstrated to exclusively recognise CD195 phosphorylated at Ser 349 Human CD195 is a member of the G protein coupled superfamily of receptors, This item recognises a band of approximately 40kD on Western blots of RBL-CCR5 cell lysates, This particular antibody might cross react with speacies outside of the listed ones, a cell surface antigen of approximately 40kD, also known as CCR5, which acts as a receptor for a number of chemokines including RANTES and also serves as a co-receptor for the entry of HIV into cells, CD195 This item is specific for human CD195 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
ELISA (EIA), Flow Cytometry (FACS), Immunofluorescence (IF), Western Blot (WB) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD195 (pSer349) |
| Short name: |
MOUSE Anti-HUMAN CD195 (pSer349) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens CD195 (pSer349) (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
1606 |
| Gene: |
CCR5 |
More about : CCR5 |
| Long gene name: |
C-C motif chemokine receptor 5 (gene/pseudogene) |
| Synonyms gene: |
CMKBR5 |
| Synonyms gene name: |
chemokine (C-C motif) receptor 5 chemokine (C-C motif) receptor 5 (gene/pseudogene) |
| Synonyms: |
CKR-5 CC-CKR-5 CKR5 CD195 IDDM22 |
| Locus: |
3p21, 31 |
| Discovery year: |
1996-05-15 |
| Entrez gene record: |
1234 |
| Pubmed identfication: |
8639485 |
| RefSeq identity: |
NM_000579 |
| Classification: |
CD molecules C-C motif chemokine receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000133481 |