| Also known as: |
CD127 |
| Other names: |
IL-7 receptor alpha chain, IL-7 receptor subunit alpha, IL-7R subunit alpha, IL-7R-alpha, IL-7RA, Interleukin-7 receptor subunit alpha, N/A, interleukin 7 receptor, interleukin 7 receptor alpha chain, interleukin-7 receptor subunit alpha, interleukin-7 receptor subunit alpha |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD127 |
| Other gene names: |
CD127, IL-7 receptor subunit alpha, IL-7R subunit alpha, IL-7R-alpha, IL-7RA, IL-7Ralpha, Il7r, Il7r |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2b |
| Clone: |
SB/199 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
CD127 is a 65-75kD transmembrane glycoprotein that associates with the interleukin-2 receptor gamma chain to form the functional high affinity IL-7 receptor, CD127 is expressed on lymphoid precursors in the bone marrow, CD127 is the specific receptor for IL-7 and the IL-7 receptor plays a critical role in lymphoid development, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, T-cells and monocytes, This particular antibody might cross react with speacies outside of the listed ones, a subpopulation of thymocytes, pro-B cells, which is also known as CD127, CD127 This item recognises the alpha chain of the murine interleukin-7 receptor (IL-7R) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Flow Cytometry (FACS) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD127 |
| Short name: |
RAT ANTI MOUSE CD127 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RAT antibody to MOUSE CD127 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6024 |
| Gene: |
IL7R |
More about : IL7R |
| Long gene name: |
interleukin 7 receptor |
| Synonyms: |
CD127 |
| Locus: |
5p13, 2 |
| Discovery year: |
1991-08-07 |
| GenBank acession: |
M29696 |
| Entrez gene record: |
3575 |
| Pubmed identfication: |
2317865 |
| Classification: |
CD molecules Fibronectin type III domain containing Interleukin receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000090791 |
| Locus Specific Databases: |
IL7Rbase: Mutation registry for Interleukin-7 receptor &, deficiency LRG_74 , #945 |