| known also as: |
Anti-RABBIT ANTI HUMAN CD82 (C-TERMINAL) |
| known also as: |
RABBIT ANTI HUMAN CD82 (C-TERMINAL) |
| known also as: |
Lapin ANTI Homo sapiens CD82 (C-TERMINAL) |
| known also as: |
CD82 |
| Other names: |
C33 antigen, C33 antigen, CD82 antigen, CD82 antigen, CD82 antigen (R2 leukocyte antigen, CD82 molecule, IA4, Inducible membrane protein R2, Metastasis suppressor Kangai-1, Suppressor of tumorigenicity 6 protein, Tetraspanin-27, antigen detected by monoclonal and antibody IA4)), inducible membrane protein R2, kangai 1 (suppression of tumorigenicity 6, metastasis suppressor Kangai-1, prostate, tetraspanin-27, tspan-27, CD82 antigen isoform 2 |
| Gene name: |
CD82 |
| Other gene names: |
4F9, C33, CD82, GR15, IA4, KAI1, KAI1, R2, SAR2, SAR2, ST6, ST6, TSPAN27, TSPAN27, Tspan-27, CD82 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
It has been hypothesized that tumour cells dislodged from the primary tumour and expressing CD82 interact with CD234 expressed on vascular cells, Loss of CD82 and p53 is correlated with poor prognosis for patients with prostate and other forms of cancer, SAR2 and TSPAN27, Tumour cells that have lost CD82 expression can proliferate and potentially give rise to metastases, _x000D__x000D_CD82 has been identified as a cancer metastasis suppressor protein, _x000D__x000D_It has been demonstrated that at least two isoforms of CD82 exist, _x000D__x000D_Research has demonstrated that CD82 interacts with CD234 (DARC), a multi-pass membrane protein of approximately 30kDa belonging to the tetraspanin (TM4SF) family, also known as KAI1, its expression is down regulated during tumour progression, transmitting a senescent signal to the tumour cells, while ubiquitously expressed at moderate to high levels in many normal tissues, CD82 This item recognises the human CD82 antigen |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Western Blot (WB), Immunohistology - Paraffin (IHC) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
CD82 |
| Short name: |
Anti-HUMAN CD82 (C-TERMINAL) |
| Alternative name: |
sapiens CD82 molecule (C-TERMINAL), antibody to-H |
| Alternative to gene target: |
4F9 and C33 and GR15 and IA4 and KAI1 and R2 and SAR2 and ST6 and TSPAN27, CD82 and IDBG-40873 and ENSG00000085117 and 3732, CD82 and IDBG-636903 and ENSBTAG00000031252 and 100335281, Cd82 and IDBG-192552 and ENSMUSG00000027215 and 12521, Plasma membranes, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005515 : protein binding, this GO :0005515 : protein binding, 506713, CD82 molecule |
| Identity: |
6210 |
| Gene: |
CD82 |
More about : CD82 |
| Long gene name: |
CD82 molecule |
| Synonyms gene: |
ST6 KAI1 |
| Synonyms gene name: |
CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4)) CD82 antigen , kangai 1 (suppression of tumorigenicity 6, prostate |
| Synonyms: |
R2 IA4 TSPAN27 |
| Synonyms name: |
suppression of tumorigenicity 6 R2 leukocyte antigen |
| Locus: |
11p11, 2 |
| Discovery year: |
1994-01-10 |
| GenBank acession: |
U20770 |
| Entrez gene record: |
3732 |
| Classification: |
CD molecules Tetraspanins |
| Havana BLAST/BLAT: |
OTTHUMG00000166472 |