| known also as: |
Anti-SHEEP ANTI HUMAN ERYTHROPOIETIN RECEPTOR |
| known also as: |
Ovine ANTI HUMAN ERYTHROPOIETIN RECEPTOR |
| known also as: |
Ovinae ANTI Homo sapiens ERYTHROPOIETIN RECEPTOR |
| known also as: |
ERYTHROPOIETIN RECEPTOR |
| Other names: |
Erythropoietin receptor, N/A, erythropoietin receptor, erythropoietin receptor, erythropoietin receptor |
| Other gene names: |
EPO-R, EPO-R, EPOR, EPOR |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Sheep |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
Binding of EPO to EPOR, EPOR-S and EPOR-T, Removal of Sodium Azide is recommended prior to use in functional assays, Several isoforms of EPOR exist: EPOR-F, The recommended concentration for functional assays is 500ug/ml, This item has been reported for use in functional studies, This item has been shown to block Iodine<, a type I transmembrane protein and member of the type I cytokine receptor family, and a functional EPOR is found on endothelial cells and cardiomyocytes within the cardiovascular system, and in some cell types activation of STAT1 and STAT3, and maintain progenitor survival, expressed by erythroid cells and erythroid progenitor cells, labelled erythropoietin ligand binding using erythroleukemia cell line TF-1 with 3000 EPOR/cell in neutralization studies This item is reported as suitable for use in immunocytochemistry, results in the dimerization of the EPOR and the triggering of the JAK2/STAT5 signaling cascade, suggesting a role in cardiac function, which acts as a receptor for erythropoietin (EPO) to mediate erythroblast proliferation and differentiation, /sup>, 125<, ERYTHROPOIETIN RECEPTOR This item recognises Erythropoietin Receptor (EPOR), sup> |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
DO NOT FREEZE, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
ERYTHROPOIETIN RECEPTOR |
| Short name: |
SHEEP ANTI HUMAN ERYTHROPOIETIN RECEPTOR Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens ERYTHROPOIETIN RECEPTOR (Antibody to), ovine antibody to H |
| Alternative technique: |
antibodies |
| Identity: |
3416 |
| Gene: |
EPOR |
More about : EPOR |
| Long gene name: |
erythropoietin receptor |
| Locus: |
19p13, 2 |
| Discovery year: |
1990-05-14 |
| GenBank acession: |
M34986 |
| Entrez gene record: |
2057 |
| Classification: |
Fibronectin type III domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000182027 |