| known also as: |
Anti-GOAT ANTI HUMAN CD192 (N-TERMINAL) |
| known also as: |
Caprine ANTI HUMAN CD192 (N-TERMINAL) |
| known also as: |
Caprinae ANTI Homo sapiens CD192 (N-TERMINAL) |
| known also as: |
CD192 |
| Other names: |
C-C chemokine receptor type 2, C-C chemokine receptor type 2, MCP-1 receptor, Monocyte chemoattractant protein 1 receptor, chemokine (C-C motif) receptor 2, monocyte chemoattractant protein 1 receptor, monocyte chemotactic protein 1 receptor, C-C chemokine receptor type 2 isoform A |
| Gene name: |
CD192 |
| Other gene names: |
C-C CKR-2, CC-CKR-2, CC-CKR-2, CCR-2, CCR-2, CCR2, CCR2, CCR2A, CCR2B, CD192, CKR2, CKR2A, CKR2B, CMKBR2, CMKBR2, MCP-1-R, MCP-1-R, CCR2 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Goat |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
CD192 acts as a co-receptor with CD4 for HIV1 infection, MCP-3 and MCP-4, _x000D__x000D_Interaction between CD192 and MCP-1 initiates chemotactic responses, a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, and variations in CD192 are associated with relative resistance to HIV1, otherwise known as CCR2 (C-C chemokine receptor type 2), through an increase in intracellular calcium levels, which acts as a receptor for the chemokines MCP-1 (monocyte chemoattractant protein 1), CD192 This item specifically recognises an epitope within the N-terminal (NT) region of human CD192 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Immunohistology - Paraffin (IHC), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
CD192 |
| Short name: |
GOAT ANTI HUMAN CD192 (N-TERMINAL) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens CD192 (N-TERMINAL) (Antibody to), caprine antibody to H |
| Alternative technique: |
antibodies |
| Identity: |
1603 |
| Gene: |
CCR2 |
More about : CCR2 |
| Long gene name: |
C-C motif chemokine receptor 2 |
| Synonyms gene: |
CMKBR2 |
| Synonyms gene name: |
chemokine (C-C motif) receptor 2 |
| Synonyms: |
CC-CKR-2 CKR2 MCP-1-R CD192 FLJ78302 |
| Locus: |
3p21, 31 |
| Discovery year: |
1995-05-30 |
| Entrez gene record: |
729230 |
| Pubmed identfication: |
8146186 |
| RefSeq identity: |
NM_000647 |
| Classification: |
CD molecules C-C motif chemokine receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000156466 |