| known also as: |
Anti-RABBIT ANTI HUWE1 |
| known also as: |
RABBIT ANTI HUWE1 |
| known also as: |
Lapin ANTI HUWE1 |
| known also as: |
HUWE1 |
| Other names: |
ARF-BP1, ARF-binding protein 1, ARF-binding protein 1, BJ-HCC-24 tumor antigen, E3 ubiquitin protein ligase, E3 ubiquitin-protein ligase HUWE1, E3 ubiquitin-protein ligase HUWE1, HECT, HECT, HECT domain protein LASU1, HectH9, Homologous to E6AP carboxyl terminus homologous protein 9, LASU1, Large structure of UREB1, Mcl-1 ubiquitin ligase E3, Mcl-1 ubiquitin ligase E3, Mule, UBA and WWE domain containing 1, UBA and WWE domain-containing protein 1, URE-binding protein 1, Upstream regulatory element-binding protein 1, homologous to E6AP carboxyl terminus homologous protein 9, large structure of UREB1, upstream regulatory element-binding protein 1, E3 ubiquitin-protein ligase HUWE1 |
| Gene name: |
HUWE1 |
| Other gene names: |
ARF-BP1, ARF-BP1, HECTH9, HSPC272, HUWE1, HectH9, Ib772, KIAA0312, KIAA1578, LASU1, LASU1, MULE, Mule, URE-B1, URE-B1, UREB1, UREB1, HUWE1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
Binds to an upstream initiator-like sequence in the preprodynorphin gene, H2A, H2B, H3 and H4, Research indicates that HUWE1 regulates the abundance of CDC6 after DNA damage by polyubiquitinating and targeting CDC6 to degradation, _x000D_HUWE1 is a novel E3 ubiquitin-protein ligase involved with mediating ubiquitination and subsequent proteasomal degradation of target proteins, _x000D_HUWE1 is involved in apoptosis through catalyzation of the polyubiquitination and degradation of MCL1, a 148kDa DNA binding protein, ubiquitination of the p53 tumor suppressor and core histones including H1, HUWE1 This item specifically recognises human HUWE1 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, Total protein concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Immunohistology - Paraffin (IHC), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
HUWE1 |
| Short name: |
Anti-HUWE1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
antibody to-HUWE1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
30892 |
| Gene: |
HUWE1 |
More about : HUWE1 |
| Long gene name: |
E3 ubiquitin protein ligase , HECT, UBA and WWE domain containing 1 |
| Synonyms gene name: |
HECT, UBA and WWE domain containing 1 |
| Synonyms: |
Ib772 KIAA0312 UREB1 |
| Locus: |
Xp11, 22 |
| Discovery year: |
2005-02-01 |
| GenBank acession: |
AB071605 |
| Entrez gene record: |
10075 |
| Pubmed identfication: |
9205841 10998601 |
| RefSeq identity: |
XM_497119 |
| Havana BLAST/BLAT: |
OTTHUMG00000021617 |
| Locus Specific Databases: |
Mental Retardation database |