| known also as: |
Anti-GOAT ANTI HUMAN CD196 |
| known also as: |
Caprine ANTI HUMAN CD196 |
| known also as: |
Caprinae ANTI Homo sapiens CD196 |
| known also as: |
CD196 |
| Other names: |
C-C chemokine receptor type 6, C-C chemokine receptor type 6, KY411, chemokine (C-C motif) receptor 6, C-C chemokine receptor type 6 isoform A |
| Gene name: |
CD196 |
| Other gene names: |
C-C CKR-6, CC-CKR-6, CC-CKR-6, CCR-6, CCR-6, Ccr6, Cmkbr6, Cmkbr6, KY411, Ccr6 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Goat |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
CD196 acts as a co-receptor for HIV1 infection, _x000D__x000D_CD196 is preferentially expressed by B cells, _x000D__x000D_This item cross-reacts with mouse CD196, a selective chemoattractant which induces calcium flux in CD196-expressing lymphocytes, a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, and is selectively expressed by mucosa-associated non-Hodgkin's lymphoma, making the interaction between CD196 and LARC a potential therapeutic target in these malignancies, memory T cells and immature dendritic cells and plays an important role in B lineage maturation and antigen-driven B cell differentiation, otherwise known as CCR6 (C-C chemokine receptor type 6), where linear epitopes are accessible, which acts as a specific receptor for the C-C chemokine LARC (Liver and activation-regulated chemokine)/MIP-3alpha, CD196 This item recognises human CD196 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Immunohistology - Paraffin (IHC), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
CD196 |
| Short name: |
GOAT ANTI HUMAN CD196 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens CD196 (Antibody to), caprine antibody to H |
| Alternative technique: |
antibodies |
| Identity: |
1607 |
| Gene: |
CCR6 |
More about : CCR6 |
| Long gene name: |
C-C motif chemokine receptor 6 |
| Synonyms gene: |
STRL22 |
| Synonyms gene name: |
chemokine (C-C motif) receptor 6 |
| Synonyms: |
CKR-L3 GPR-CY4 CMKBR6 GPR29 DRY-6 DCR2 BN-1 CD196 |
| Locus: |
6q27 |
| Discovery year: |
1997-04-21 |
| GenBank acession: |
U68030 |
| Entrez gene record: |
1235 |
| Pubmed identfication: |
8886020 |
| Classification: |
CD molecules C-C motif chemokine receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000016015 |