| known also as: |
Anti-GOAT ANTI HUMAN FOXC2 (C-TERMINAL) |
| known also as: |
Caprine ANTI HUMAN FOXC2 (C-TERMINAL) |
| known also as: |
Caprinae ANTI Homo sapiens FOXC2 (C-TERMINAL) |
| known also as: |
FOXC2 |
| Other names: |
Drosophila, Forkhead box protein C2, Forkhead-related protein FKHL14, MFH-1, MFH-1 protein, Mesenchyme fork head protein 1, Transcription factor FKH-14, forkhead, forkhead box C2 (MFH-1, forkhead box protein C2, forkhead-related protein FKHL14, homolog-like 14, mesenchyme fork head protein 1, mesenchyme forkhead 1), transcription factor FKH-14, forkhead box protein C2, mesenchyme forkhead 1 |
| Gene name: |
FOXC2 |
| Other gene names: |
FKHL14, FKHL14, FOXC2, LD, MFH-1, MFH-1 protein, MFH1, MFH1, FOXC2 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Goat |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
_x000D__x000D_Mutations in the FOXC2 gene are responsible for the chronic disabling condition lymphedema hereditary type 2 (LYH2) and lymphedema-distichiasis (LYD), a member of the Forkhead family of transcription factors, and with the regulation of vascular/lymphatic vessel formation in cardiovascular development and disease, linked with the fate of mesenchymal cells during embryogenesis, otherwise known as Forkhead box C2, FOXC2 This item specifically recognises an epitope within the C-terminal (CT) region of human FOXC2 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
IgG concentration 500ug/1000ul |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
FOXC2 |
| Short name: |
GOAT ANTI HUMAN FOXC2 (C-TERMINAL) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
mesenchyme forkhead 1) (C-TERMINAL) (Antibody to), sapiens forkhead box complement component 2 (MFH-1, caprine antibody to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0007498 and mesoderm development and biological process this GO :0007507 and heart development and biological process this GO :0008283 and cell proliferation and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0009725 and response to hormone and biological process this GO :0010595 and positive regulation of endothelial cell migration and biological process this GO :0014032 and neural crest cell development and biological process this GO :0030199 and collagen fibril organization and biological process this GO :0031490 and chromatin DNA binding and molecular function this GO :0033630 and positive regulation of cell adhesion mediated by integrin and biological process this GO :0035050 and embryonic heart tube development and biological process this GO :0035470 and positive regulation of vascular wound healing and biological process this GO :0043010 and camera-type eye development and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046620 and regulation of organ growth and biological process this GO :0048010 and vascular endothelial growth factor receptor signaling pathway and biological process this GO :0048341 and paraxial mesoderm formation and biological process this GO :0048343 and paraxial mesodermal cell fate commitment and biological process this GO :0048701 and embryonic cranial skeleton morphogenesis and biological process this GO :0048703 and embryonic viscerocranium morphogenesis and biological process this GO :0048704 and embryonic skeletal system morphogenesis and biological process this GO :0048844 and artery morphogenesis and biological process this GO :0050880 and regulation of blood vessel size and biological process this GO :0055010 and ventricular cardiac muscle tissue morphogenesis and biological process this GO :0060038 and cardiac muscle cell proliferation and biological process this GO :0072011 and glomerular endothelium development and biological process this GO :0072112 and glomerular visceral epithelial cell differentiation and biological process this GO :0072144 and glomerular mesangial cell development and biological process this GO :0090050 and positive regulation of cell migration involved in sprouting angiogenesis and biological process this GO :1902257 and negative regulation of apoptotic process involved in outflow tract morphogenesis and biological process, FKHL14 and LD and MFH-1 and MFH1, FOXC2 and IDBG-45466 and ENSG00000176692 and 2303, FOXC2 and IDBG-630185 and ENSBTAG00000012465 and 507300, Foxc2 and IDBG-196604 and ENSMUSG00000046714 and 14234, mesenchyme forkhead 1), nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001501 and skeletal system development and biological process this GO :0001503 and ossification and biological process this GO :0001568 and blood vessel development and biological process this GO :0001569 and patterning of blood vessels and biological process this GO :0001656 and metanephros development and biological process this GO :0001657 and ureteric bud development and biological process this GO :0001756 and somitogenesis and biological process this GO :0001822 and kidney development and biological process this GO :0001945 and lymph vessel development and biological process this GO :0001946 and lymphangiogenesis and biological process this GO :0001974 and blood vessel remodeling and biological process this GO :0003007 and heart morphogenesis and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003705 and RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and molecular function this GO :0005634 and nucleus and cellular component this GO :0006355 and regulation of transcription, this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0003705 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and also this GO :0031490 : chromatin DNA binding and also this GO :0043565 : sequence-specific DNA binding and also this GO :0044212 : transcription regulatory region DNA binding, this GO :0003677 : DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0003705 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, this GO :0031490 : chromatin DNA binding, this GO :0043565 : sequence-specific DNA binding, this GO :0044212 : transcription regulatory region DNA binding, transcription regulatory region DNA binding, forkhead box C2 (MFH-1 |
| Identity: |
3801 |
| Gene: |
FOXC2 |
More about : FOXC2 |
| Long gene name: |
forkhead box C2 |
| Synonyms gene: |
FKHL14 |
| Synonyms gene name: |
forkhead box C2 (MFH-1, mesenchyme forkhead 1) |
| Synonyms: |
MFH-1 |
| Synonyms name: |
mesenchyme forkhead 1 |
| Locus: |
16q24, 1 |
| Discovery year: |
1997-02-14 |
| GenBank acession: |
Y08223 |
| Entrez gene record: |
2303 |
| Pubmed identfication: |
9169153 8674414 |
| RefSeq identity: |
NM_005251 |
| Classification: |
Forkhead boxes |
| Havana BLAST/BLAT: |
OTTHUMG00000137652 |