| known also as: |
Anti-GOAT ANTI HUMAN NQO1 (C-TERMINAL) |
| known also as: |
Caprine ANTI HUMAN NQO1 (C-TERMINAL) |
| known also as: |
Caprinae ANTI Homo sapiens NQO1 (C-TERMINAL) |
| known also as: |
NQO1 |
| Other names: |
Azoreductase, DT-diaphorase, DT-diaphorase, DTD, Menadione reductase, NAD(P)H dehydrogenase, NAD(P)H dehydrogenase [quinone] 1, NAD(P)H dehydrogenase [quinone] 1, NAD(P)H dehydrogenase [quinone] 1, NAD(P)H:Quinone acceptor oxidoreductase type 1, NAD(P)H:menadione oxidoreductase 1, NAD(P)H:quinone oxidoreductase 1, NAD(P)H:quinone oxidoreductase 1, NAD(P)H:quinone oxireductase, Phylloquinone reductase, Quinone reductase 1, azoreductase, diaphorase (NADH/NADPH) (cytochrome b-5 reductase), diaphorase-4, dioxin-inducible 1, menadione reductase, phylloquinone reductase, quinone 1, quinone reductase 1, NAD(P)H dehydrogenase |
| Gene name: |
NQO1 |
| Other gene names: |
DHQU, DIA4, DIA4, DTD, DTD, NMOR1, NMOR1, NMORI, NQO1, QR1, QR1, NQO1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Goat |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
Mutations in the NQO1 gene are associated with an increased risk of certain cancers, The ability of NQO1 to bioactivate anti-tumour quinones including mitomycin C and diaziquone, _x000D__x000D_NQO1 is expressed in a wide range of tissues and is overexpressed in many human tumours including lung, a cytosolic flavoenzyme and member of the NAD(P)H dehydrogenase (quinone) family, and an increased risk of leukaemia has been associated with diminished NQO1 activity and the NQO1 *2 allele, brain, colon and breast, has become a focus area for chemotherapeutic studies, involved in detoxification, liver, which catalyzes the two-electron reduction of quinones to hydroquinones, NQO1 This item specifically recognises an epitope within the C-terminal (CT) region of human NQO1 (NAD(P)H:quinone oxidoreductase 1) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
IgG concentration 500ug/1000ul |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
NQO1 |
| Short name: |
GOAT ANTI HUMAN NQO1 (C-TERMINAL) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
quinone 1 (C-TERMINAL) (Antibody to), sapiens Nicotinamide adenine dinucleotide(P)H dehydrogenase, caprine antibody to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Cytoplasm, DHQU and DIA4 and DTD and NMOR1 and NMORI and QR1, NQO1 and IDBG-39427 and ENSG00000181019 and 1728, NQO1 and IDBG-634590 and ENSBTAG00000020632 and 519632, Nqo1 and IDBG-190808 and ENSMUSG00000003849 and 18104, acting on NAD(P)H, acting on NAD(P)H and also this GO :0004784 : superoxide dismutase activity and also this GO :0005515 : protein binding and also this GO :0016491 : oxidoreductase activity and also this GO :0044822 : poly(A) RNA binding, acting on NAD(P)H and molecular function this GO :0004784 and superoxide dismutase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006521 and regulation of cellular amino acid metabolic process and biological process this GO :0006801 and superoxide metabolic process and biological process this GO :0006805 and xenobiotic metabolic process and biological process this GO :0006809 and nitric oxide biosynthetic process and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0007271 and synaptic transmission, cholinergic and biological process this GO :0007568 and aging and biological process this GO :0007584 and response to nutrient and biological process this GO :0009636 and response to toxic substance and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0016491 and oxidoreductase activity and molecular function this GO :0019430 and removal of superoxide radicals and biological process this GO :0032355 and response to estradiol and biological process this GO :0034641 and cellular nitrogen compound metabolic process and biological process this GO :0043025 and neuronal cell body and cellular component this GO :0043086 and negative regulation of catalytic activity and biological process this GO :0043525 and positive regulation of neuron apoptotic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045471 and response to ethanol and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, cytochrome-b5 reductase activity, quinone 1, this GO :0003955 and NAD(P)H dehydrogenase (quinone) activity and molecular function this GO :0004128 and cytochrome-b5 reductase activity, this GO :0003955 : NAD(P)H dehydrogenase (quinone) activity, this GO :0003955 : NAD(P)H dehydrogenase (quinone) activity and also this GO :0004128 : cytochrome-b5 reductase activity, this GO :0004128 : cytochrome-b5 reductase activity, this GO :0004784 : superoxide dismutase activity, this GO :0005515 : protein binding, this GO :0016491 : oxidoreductase activity, this GO :0044822 : poly(A) RNA binding, NAD(P)H dehydrogenase |
| Identity: |
2874 |
| Gene: |
NQO1 |
More about : NQO1 |
| Long gene name: |
NAD(P)H quinone dehydrogenase 1 |
| Synonyms gene: |
NMOR1 DIA4 |
| Synonyms gene name: |
diaphorase (NADH/NADPH) (cytochrome b-5 reductase) NAD(P)H dehydrogenase, quinone 1 |
| Synonyms: |
DHQU QR1 DTD |
| Locus: |
16q22, 1 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
M81600 |
| Entrez gene record: |
1728 |
| Pubmed identfication: |
2843525 |
| Havana BLAST/BLAT: |
OTTHUMG00000137575 |