| Also known as: |
CD140b |
| Other names: |
Beta platelet-derived growth factor receptor, Beta-type platelet-derived growth factor receptor, CD140 antigen-like family member B, CD140 antigen-like family member B, PDGF-R-beta, PDGFR-beta, Platelet-derived growth factor receptor 1, Platelet-derived growth factor receptor beta, beta polypeptide, beta-type platelet-derived growth factor receptor, platelet-derived growth factor receptor, platelet-derived growth factor receptor 1, platelet-derived growth factor receptor beta, platelet-derived growth factor receptor beta |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD140b |
| Other gene names: |
CD140B, IBGC4, JTK12, PDGF-R-beta, PDGFR, PDGFR, PDGFR-1, PDGFR-1, PDGFR-beta, PDGFR1, PDGFR1, PDGFRB, PDGFRB |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
PR7212 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Binding of PDGF-BB induces receptor homodimerization or heterodimerization with PDGF receptor alpha, PDGF receptor beta is a member of the class III receptor tyrosine kinase family that also includes M-CSF receptor, SCF receptor and Flt-3, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This item does not recognize PDGF receptor alpha, This particular antibody might cross react with speacies outside of the listed ones, This was confirmed in binding studies using several different cell lines and by its ability to immunoprecipitate PDGF receptor beta complexed with <, /sup>, 125<, CD140b This item is specific for the extracellular domain of the human PDGF receptor beta subunit, I-PDGF-BB, sup> |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistology - Frozen (IHC), Immunoprecipitation (IP), Western Blot (WB), Immunohistology - Paraffin (IHC) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD140b |
| Short name: |
MOUSE Anti-HUMAN CD140b Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens CD140b (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
8804 |
| Gene: |
PDGFRB |
More about : PDGFRB |
| Long gene name: |
platelet derived growth factor receptor beta |
| Synonyms gene: |
PDGFR |
| Synonyms gene name: |
beta polypeptide , platelet-derived growth factor receptor |
| Synonyms: |
JTK12 CD140b PDGFR1 |
| Locus: |
5q32 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
M21616 |
| Entrez gene record: |
5159 |
| RefSeq identity: |
NM_002609 |
| Classification: |
I-set domain containing CD molecules Immunoglobulin like domain containing Receptor Tyrosine Kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000130053 |