| Also known as: |
EPSTEIN-BARR VIRUS NUCLEAR ANTIGEN |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
0211 (6F9/60) |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Viral |
| Specificity and cross-reactivity: |
EBNA1 is a viral protein required to maintain the EBV genomes in _x000D__x000D_proliferating cells, EBNA1 is able to avoid detection by cytotoxic _x000D__x000D_T-lymphocytes which enables the persistence of latently infected cells that express EBNA1 in the absence of other EBV antigens, It fulfils this role by binding to recognition sites in the FR and DS elements of the latent origin of DNA _x000D__x000D_replication (oriP) within the episome, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, This promotes DNA replication and is involved with the partitioning of the episome _x000D__x000D_during cell division and the activation of other viral latency genes, EPSTEIN-BARR VIRUS NUCLEAR ANTIGEN This item recognises the C-terminal region (~ last 100 amino acids) of Epstein-Barr virus nuclear antigen 1 (EBNA1) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
1 miligram per 1 mililiter, IgG concentration 0 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Immunohistology - Paraffin (IHC), Western Blot (WB), Immunoprecipitation (IP) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
EPSTEIN-BARR VIRUS |
| Short name: |
MOUSE Anti-EPSTEIN-BARR VIRUS NUCLEAR ANTIGEN Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MOUSE antibody to-EPSTEIN-BARR VIRUS NUCLEAR protein (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3129 |
| Gene: |
EBI3 |
More about : EBI3 |
| Long gene name: |
Epstein-Barr virus induced 3 |
| Synonyms: |
IL27B IL35B |
| Synonyms name: |
IL27 subunit IL35 subunit |
| Locus: |
19p13, 3 |
| Discovery year: |
2000-05-02 |
| GenBank acession: |
L08187 |
| Entrez gene record: |
10148 |
| Pubmed identfication: |
8551575 |
| Classification: |
Minor histocompatibility antigens Fibronectin type III domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000181866 |