| Also known as: |
C3b |
| Other names: |
ASP, Alternative name(s):, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1Cleaved into the following 11 chains:Complement C3 beta chainComplement C3 alpha chainC3a anaphylatoxinAcylation stimulating protein, C3a anaphylatoxin, C3adesArg, Complement C3, acylation-stimulating protein cleavage product, complement C3, complement component 3, complement component C3, complement component C3a, complement component C3b, prepro-C3, complement C3 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
C3b |
| Other gene names: |
AHUS5, ARMD9, ASP, ASP, C3, C3a, C3b, CPAMD1, CPAMD1, C3 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
H11 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
C3 is cleaved by C3-convertase creating C3a and C3b, It does not react with the anaphylatoxin C3a_x000D_or the fragment C3d and does not inhibit the haemolytic function of C3, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The antibody is directed to a determinant present on the betachain of the C3 molecule (Western blot), This particular antibody might cross react with speacies outside of the listed ones, part of the complement system, which binds to the surface of pathogens leading to their destruction by phagocytic cells, C3b This item is specific for C3b, _x000D_, _x000D_This antibody recognizes a determinant present on native (circulating) C3 and on the fragments C3b and C3c |
| Form/Appearance: |
Purified (Purified IgG - lyophilised) |
| Concentration: |
IgG concentration 50 ug/ml after reconstitution |
| Storage and shipping: |
After reconstitution Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term, If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 12 months from date of reconstitution, Temperature variations in the range between +1C to +7C are tolerable, the antibody should be stored undiluted, Prior to reconstitution Keep the antibody refrigerated at +4 degrees Celsius, Storage in frost-free freezers is not recommended |
| Tested applications:: |
Western Blot (WB), Immunohistology - Frozen (IHC) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
C3b |
| Short name: |
MOUSE Anti-HUMAN C3b Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens C3b (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
1318 |
| Gene: |
C3 |
More about : C3 |
| Long gene name: |
complement C3 |
| Synonyms gene name: |
complement component 3 |
| Synonyms: |
CPAMD1 ARMD9 C3a C3b |
| Synonyms name: |
C3a anaphylatoxin complement component C3a complement component C3b prepro-C3 |
| Locus: |
19p13, 3 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
J04763 |
| Entrez gene record: |
718 |
| RefSeq identity: |
NM_000064 |
| Classification: |
Endogenous ligands Complement system C3 and PZP like, alpha-2-macroglobulin domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000150335 |
| Locus Specific Databases: |
C3base: Mutation registry for C3 deficiency LRG_27 |