| known also as: |
Anti-RABBIT ANTI HUMAN TOSO (C-TERMINAL) |
| known also as: |
RABBIT ANTI HUMAN TOSO (C-TERMINAL) |
| known also as: |
Lapin ANTI Homo sapiens TOSO (C-TERMINAL) |
| known also as: |
TOSO |
| Other names: |
Fas apoptotic inhibitory molecule 3, Fas apoptotic inhibitory molecule 3, Fc mu receptor, IgM Fc receptor, Regulator of Fas-induced apoptosis Toso, fas apoptotic inhibitory molecule 3, immunoglobulin mu Fc receptor, regulator of Fas-induced apoptosis Toso, fas apoptotic inhibitory molecule 3 isoform b |
| Gene name: |
TOSO |
| Other gene names: |
FAIM3, FCMR, TOSO, TOSO, FAIM3 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
Despite its predicted molecular weight, FADD-, Toso expressing cells have increased resistance to Fas-, Toso is expressed by lymphoid and haematopoietic cells and is up-regulated by T-cell activation, Toso is membrane bound, Toso often migrates at 60kDa in SDS PAGE, _x000D_ _x000D_Toso is a potential proto-oncogene, also known as Fas Apoptotic Inhibitory Molecule 3 (FAIM3), and TNFalpha-induced apoptosis, and could be a therapeutic target for use in the treatment of autoimmune diseases, and is thought to directly bind to FADD, disrupting DISC formation and thus inhibiting caspase-8 activation, TOSO Detects an epitope within the C-terminal (CT) region of human Toso |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
5 mg/ml, IgG concentration 0 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
TOSO |
| Short name: |
Anti-HUMAN TOSO (C-TERMINAL) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens TOSO (C-TERMINAL) (Antibody to), antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
14315 |
| Gene: |
FCMR |
More about : FCMR |
| Long gene name: |
Fc fragment of IgM receptor |
| Synonyms gene: |
FAIM3 |
| Synonyms gene name: |
Fas apoptotic inhibitory molecule 3 |
| Synonyms: |
TOSO |
| Locus: |
1q32, 1 |
| Discovery year: |
2005-04-04 |
| GenBank acession: |
AF057557 |
| Entrez gene record: |
9214 |
| Pubmed identfication: |
9586636 1563211 25888699 |
| RefSeq identity: |
NM_005449 |
| Classification: |
Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000036457 |