| Also known as: |
CD8 BETA |
| Other names: |
CD8 antigen, CD8 antigen, CD8 antigen 37 kDa chain, CD8 antigen 37 kDa chain, CD8 antigen beta-chain, CD8b molecule, OX-8 membrane antigen, OX-8 membrane antigen, T-cell surface glycoprotein CD8 beta chain, T-cell surface glycoprotein CD8 beta chain, beta chain, beta-chain, T-cell surface glycoprotein CD8 beta chain |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD8 BETA |
| Other gene names: |
Cd8b, Cd8b1, Cd8b1, Cd8b |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
341 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Rat (Rattus norvegicus) |
| Specificity and cross-reactivity: |
CD8b is not expressed by NK cells or by intestinal intraepithelial T cells, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This item is reported to block proliferative and cytotoxic responses of CD8 +ve effector cells <, This particular antibody might cross react with speacies outside of the listed ones, expressed on thymocytes and peripheral cytotoxic/suppressor cells, /i>, CD8 BETA This item recognises the b chain of the rat CD8 cell surface antigen, i>, in vitro< |
| Form/Appearance: |
FITC (Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid) |
| Concentration: |
1 miligram per 1 mililiter, IgG concentration 0 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, for longer, for one month or the antibody should be stored at -20 degrees Celsius, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius |
| Tested applications:: |
Flow Cytometry (FACS) |
| Properties: |
FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, MBS mono FITC is highly sensitive to pH extremes, This MBS mono Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Description: |
This transmembrane glycoprotein is detected by monoclonals and has a lot of clones available with different affinity, Cytotoxic T cells cluster differentiators for flow cytometry |
| Conjugation: |
Anti-FITC Antibody |
| Gene target: |
CD8 BETA: |
| Short name: |
MOUSE Anti-RAT CD8 BETA:FITC Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, Antibody |
| Label: |
FITC |
| Alternative name: |
MOUSE antibody to-RAT CD8 b:fluorecein (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1706 |
| Gene: |
CD8A |
More about : CD8A |
| Long gene name: |
CD8a molecule |
| Synonyms gene: |
CD8 |
| Synonyms gene name: |
CD8 antigen, alpha polypeptide (p32) T-cell surface glycoprotein CD8 alpha chain |
| Locus: |
2p11, 2 |
| Discovery year: |
1986-01-01 |
| Entrez gene record: |
925 |
| Pubmed identfication: |
1541829 |
| RefSeq identity: |
NM_001768 |
| Classification: |
CD molecules V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000130265 |
| Locus Specific Databases: |
CD8Abase: Mutation registry for CD8 deficiency LRG_44 |