| known also as: |
Anti-RABBIT ANTI MCM5 |
| known also as: |
RABBIT ANTI MCM5 |
| known also as: |
Lapin ANTI MCM5 |
| known also as: |
MCM5 |
| Other names: |
CDC46 homolog, CDC46 homolog, DNA replication licensing factor MCM5, DNA replication licensing factor MCM5, MCM5 minichromosome maintenance deficient 5, P1-CDC46, cell division cycle 46, minichromosome maintenance complex component 5, minichromosome maintenance deficient 5 (cell division cycle 46), DNA replication licensing factor MCM5 |
| Gene name: |
MCM5 |
| Other gene names: |
CDC46, CDC46, MCM5, P1-CDC46, MCM5 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
The level of MCM5 is upregulated during the G1/S cell cycle phase and studies have shown a correlation between increasing levels of MCM5 and increased Stat1-mediated transcription activation in response to IFNgamma, _x000D__x000D_During the G1 phase of the cell cycle the MCM proteins, a putative DNA replicative helicase and member of the MCM family, although the latter does not appear to phosphorylate MCM5 in vitro, critical during the initiation of DNA replication, part of the pre-replicative complex which assembles at replication origins, undergo phosphorylation by kinases including cyclin dependent kinase (CDK) and Cdc7/Dbf4 (DDK), MCM5 This item specifically recognises the nuclear protein MCM5 (mini chromosome maintenance protein 5) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Immunoprecipitation (IP), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
MCM5 |
| Short name: |
Anti-MCM5 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
antibody to-MCM5 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6948 |
| Gene: |
MCM5 |
More about : MCM5 |
| Long gene name: |
minichromosome maintenance complex component 5 |
| Synonyms gene: |
CDC46 |
| Synonyms gene name: |
cell division cycle 46 (S, cerevisiae) , cerevisiae) 5 (cell division cycle 46) MCM5 minichromosome maintenance deficient 5, minichromosome maintenance deficient (S |
| Locus: |
22q12, 3 |
| Discovery year: |
1994-12-13 |
| Entrez gene record: |
4174 |
| Pubmed identfication: |
8751386 10591208 |
| Classification: |
MCM family |
| Havana BLAST/BLAT: |
OTTHUMG00000150961 |