| known also as: |
Anti-RABBIT ANTI HUMAN PTK7 (N-TERMINAL) |
| known also as: |
RABBIT ANTI HUMAN PTK7 (N-TERMINAL) |
| known also as: |
Lapin ANTI Homo sapiens PTK7 (N-TERMINAL) |
| known also as: |
PTK7 |
| Other names: |
CCK-4, Colon carcinoma kinase 4, Inactive tyrosine-protein kinase 7, PTK7 protein tyrosine kinase 7, Protein-tyrosine kinase 7, Pseudo tyrosine kinase receptor 7, Tyrosine-protein kinase-like 7, colon carcinoma kinase 4, inactive tyrosine-protein kinase 7, protein tyrosine kinase 7, pseudo tyrosine kinase receptor 7, tyrosine-protein kinase-like 7, inactive tyrosine-protein kinase 7 isoform e |
| Gene name: |
PTK7 |
| Other gene names: |
CCK-4, CCK-4, CCK4, CCK4, PTK7, PTK7 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
A loss of PTK7 expression has been observed in melanoma cell lines, In addition, It is thought to function as a cell adhesion molecule and as a novel regulator of the planar cell polarity (PCP) pathway in vertebrates, PTK7 is highly expressed in the kidney, PTK7 is not expressed in normal colon but has been detected in colon carcinomas and as such is a potential marker for tumour progression, _x000D__x000D_PTK7 may play a role in embryonic development, _x000D__x000D_Studies also suggest that PTK7 may be involved in the tumour progression, a member of the receptor tyrosine kinase family, brain, heart and skeletal muscle, liver, lung, otherwise known as Colon Carcinoma Kinase 4 (CCK4), ovaries, pancreas and melanocytes with weaker expression being detected in the thyroid gland, whereas increased levels of PTK7 have been detected in high-throughput acute myeloid leukaemia samples, PTK7 This item recognises human Protein tyrosine kinase-like 7 (PTK7) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Western Blot (WB), Immunohistology - Paraffin (IHC) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
PTK7 |
| Short name: |
Anti-HUMAN PTK7 (N-TERMINAL) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens PTK7 protein tyrosine kinase 7 (N-TERMINAL) (Antibody to), antibody to-H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CCK-4 and CCK4, Cell surfaces, PTK7 and IDBG-631557 and ENSBTAG00000012761 and 514819, PTK7 and IDBG-87768 and ENSG00000112655 and 5754, Ptk7 and IDBG-187402 and ENSMUSG00000023972 and 71461, this GO :0001736 and establishment of planar polarity and biological process this GO :0001843 and neural tube closure and biological process this GO :0003401 and axis elongation and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007155 and cell adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0010976 and positive regulation of neuron projection development and biological process this GO :0016020 and membrane and cellular component this GO :0016477 and cell migration and biological process this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004714 : transmembrane receptor protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004714 : transmembrane receptor protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0031532 and actin cytoskeleton reorganization and biological process this GO :0042060 and wound healing and biological process this GO :0045198 and establishment of epithelial cell apical/basal polarity and biological process this GO :0060026 and convergent extension and biological process this GO :0060070 and canonical Wnt signaling pathway and biological process this GO :0060484 and lung-associated mesenchyme development and biological process this GO :0071300 and cellular response to retinoic acid and biological process this GO :0090103 and cochlea morphogenesis and biological process this GO :0090179 and planar cell polarity pathway involved in neural tube closure and biological process, PTK7 protein tyrosine kinase 7 |
| Identity: |
9618 |
| Gene: |
PTK7 |
More about : PTK7 |
| Long gene name: |
protein tyrosine kinase 7 (inactive) |
| Synonyms gene name: |
PTK7 protein tyrosine kinase 7 protein tyrosine kinase 7 |
| Synonyms: |
CCK4 |
| Synonyms name: |
colon carcinoma kinase 4 |
| Locus: |
6p21, 1 |
| Discovery year: |
1992-10-02 |
| GenBank acession: |
AF447176 |
| Entrez gene record: |
5754 |
| Pubmed identfication: |
7478540 |
| RefSeq identity: |
NM_002821 |
| Classification: |
I-set domain containing Immunoglobulin like domain containing Receptor Tyrosine Kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000014721 |