| known also as: |
Anti-RABBIT ANTI HUMAN DAXX |
| known also as: |
RABBIT ANTI HUMAN DAXX |
| known also as: |
Lapin ANTI Homo sapiens DAXX |
| known also as: |
DAXX |
| Other names: |
CENP-C binding protein, Daxx, Death domain-associated protein 6, EAP1, ETS1-associated protein 1, ETS1-associated protein 1, Fas death domain-associated protein, Fas-binding protein, death domain-associated protein 6, death-associated protein 6, death-domain associated protein, fas death domain-associated protein, hDaxx, death domain-associated protein 6 isoform a |
| Gene name: |
DAXX |
| Other gene names: |
BING2, BING2, DAP6, DAP6, DAXX, EAP1, EAP1, hDaxx, DAXX |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
When in association with ASK1 kinase DAXX translocates from the nucleus to the cytoplasm, _x000D__x000D_DAXX binds specifically to the death domain of Fas and enhances Fas induced apoptosis and activates the Jun N-terminal kinase (JNK) pathway, _x000D__x000D_DAXX is predominantly a nuclear protein, a novel Fas binding protein that has been designated DAXX, where it acts as a repressor of EtsI and Pax3 transactivation, DAXX This item recognises human Death Domain-Associated Protein 6 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Western Blot (WB), Immunohistology - Paraffin (IHC) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
DAXX |
| Short name: |
Anti-HUMAN DAXX |
| Alternative name: |
sapiens death-domain associated protein, antibody to-H |
| Alternative to gene target: |
BING2 and DAP6 and EAP1, DAXX and IDBG-629026 and ENSBTAG00000016830 and 504336, DAXX and IDBG-82726 and ENSG00000204209 and 102723452, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006915 and apoptotic process and biological process this GO :0007257 and activation of JUN kinase activity and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008625 and extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :0016032 and viral process and biological process this GO :0016605 and PML body and cellular component this GO :0019899 and enzyme binding and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0030295 and protein kinase activator activity and molecular function this GO :0030521 and androgen receptor signaling pathway and biological process this GO :0031072 and heat shock protein binding and molecular function this GO :0031396 and regulation of protein ubiquitination and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0042393 and histone binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0045860 and positive regulation of protein kinase activity and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0047485 and protein N-terminus binding and molecular function this GO :0050681 and androgen receptor binding and molecular function this GO :0070603 and SWI/SNF superfamily-type complex and cellular component this GO :0097190 and apoptotic signaling pathway and biological process this GO :1901216 and positive regulation of neuron death and biological process this GO :2001235 and positive regulation of apoptotic signaling pathway and biological process, Daxx and IDBG-168138 and ENSMUSG00000002307 and 13163, androgen receptor binding, centromeric region and cellular component this GO :0000792 and heterochromatin and cellular component this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0002039 and p53 binding and molecular function this GO :0003714 and transcription corepressor activity and molecular function this GO :0005057 and receptor signaling protein activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006334 and nucleosome assembly and biological process this GO :0006338 and chromatin remodeling and biological process this GO :0006351 and transcription, nuclei, this GO :0000281 and mitotic cytokinesis and biological process this GO :0000775 and chromosome, this GO :0002039 : p53 binding, this GO :0002039 : p53 binding and also this GO :0003714 : transcription corepressor activity and also this GO :0005057 : receptor signaling protein activity and also this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0019899 : enzyme binding and also this GO :0019901 : protein kinase binding and also this GO :0030295 : protein kinase activator activity and also this GO :0031072 : heat shock protein binding and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0042393 : histone binding and also this GO :0042803 : protein homodimerization activity and also this GO :0047485 : protein N-terminus binding and also this GO :0050681 : androgen receptor binding, this GO :0003714 : transcription corepressor activity, this GO :0005057 : receptor signaling protein activity, this GO :0005515 : protein binding, this GO :0008134 : transcription factor binding, this GO :0019899 : enzyme binding, this GO :0019901 : protein kinase binding, this GO :0030295 : protein kinase activator activity, this GO :0031072 : heat shock protein binding, this GO :0031625 : ubiquitin protein ligase binding, this GO :0042393 : histone binding, this GO :0042803 : protein homodimerization activity, this GO :0047485 : protein N-terminus binding, this GO :0050681 : androgen receptor binding, 1616, death-domain associated protein |
| Identity: |
2681 |
| Gene: |
DAXX |
More about : DAXX |
| Long gene name: |
death domain associated protein |
| Synonyms gene name: |
death-associated protein 6 |
| Synonyms: |
DAP6 |
| Locus: |
6p21, 32 |
| Discovery year: |
1998-03-25 |
| GenBank acession: |
AF006041 |
| Entrez gene record: |
1616 |
| Pubmed identfication: |
9407001 9215629 |
| Havana BLAST/BLAT: |
OTTHUMG00000031203 |