| known also as: |
Anti-GOAT ANTI HUMAN LEPTIN RECEPTOR |
| known also as: |
Caprine ANTI HUMAN LEPTIN RECEPTOR |
| known also as: |
Caprinae ANTI Homo sapiens LEPTIN RECEPTOR |
| known also as: |
LEPTIN RECEPTOR |
| Other names: |
HuB219, Leptin receptor, OB receptor, OB receptor, huB219, leptin receptor, leptin receptor, leptin receptor isoform 3 |
| Other gene names: |
CD295, DB, LEP-R, LEP-R, LEPR, LEPRD, OB-R, OB-R, OBR, OBR, LEPR |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Goat |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
CD295-leptin signalling is also involved in the differential regulation of naive and memory T cell proliferation and promotes the release of pro-inflammatory cytokines, _x000D__x000D_The effects of leptin through binding to the long form of CD295 (LRb), a type 1 transmembrane glycoprotein and member of the cytokine receptor family, an obesity factor which regulates adipose-tissue mass/body weight through hypothalamic effects, and are vital for the regulation of the normal physiology of many cells, are mediated via the JAK/STAT3 signalling pathway, designated CD295, including food intake, including interferon and interleukin-2, lipid metabolism and energy expenditure, which binds with high affinity to the adipocyte-specific hormone leptin, LEPTIN RECEPTOR This item is specific for human leptin receptor |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
IgG concentration 500ug/1000ul |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Western Blot (WB), ELISA (EIA) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
LEPTIN RECEPTOR |
| Short name: |
GOAT ANTI HUMAN LEPTIN RECEPTOR Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens LEPTIN RECEPTOR (Antibody to), caprine antibody to H |
| Alternative technique: |
antibodies |
| Identity: |
6554 |
| Gene: |
LEPR |
More about : LEPR |
| Long gene name: |
leptin receptor |
| Synonyms: |
OBR CD295 |
| Locus: |
1p31, 3 |
| Discovery year: |
1996-05-09 |
| GenBank acession: |
U43168 |
| Entrez gene record: |
3953 |
| Pubmed identfication: |
8548812 8812446 |
| RefSeq identity: |
NM_002303 |
| Classification: |
CD molecules Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000009115 |
| Locus Specific Databases: |
LRG_283 |