| known also as: |
Anti-RABBIT ANTI HUMAN CD136 |
| known also as: |
RABBIT ANTI HUMAN CD136 |
| known also as: |
Lapin ANTI Homo sapiens CD136 |
| known also as: |
CD136 |
| Other names: |
CDw136, MSP receptor, MST1R variant RON30, MST1R variant RON62, Macrophage-stimulating protein receptor, PTK8 protein tyrosine kinase 8, Protein-tyrosine kinase 8, RON variant 21, RON variant E2E3, c-met-related tyrosine kinase, macrophage stimulating 1 receptor (c-met-related tyrosine kinase), macrophage-stimulating protein receptor, p185-Ron, p185-Ron, soluble RON variant 1, soluble RON variant 2, soluble RON variant 3, soluble RON variant 4, macrophage-stimulating protein receptor isoform 2 |
| Gene name: |
CD136 |
| Other gene names: |
CD136, CDw136, MSP receptor, MST1R, PTK8, PTK8, RON, RON, MST1R |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
CD136 is a member of the MET proto-oncogene family, CD136 is also required for embryonic development, In immune cells CD136 expression is restricted to certain types of tissue macrophages, _x000D__x000D_CD136 expression is significantly altered in several primary human cancers including those of the breast and colon, _x000D__x000D_CD136 is a disulfide-linked 180kD heterodimer composed of a 40kD alpha chain and a 150kD beta chain, a multifunctional cytokine that regulates cell adhesion, a receptor tyrosine kinase also known as Macrophage stimulating 1 receptor (MST1R) and RON (Recepteur d'origine nantais), and is mainly expressed in cells of epithelial origin, and is the receptor for macrophage-stimulating protein (MSP), and its activation is critical in modulating macrophage activities and preventing an excessive inflammatory response, and survival, growth, motility, CD136 This item detects CD136 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
5 mg/ml, IgG concentration 0 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Immunohistology - Paraffin (IHC) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
CD136 |
| Short name: |
Anti-HUMAN CD136 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens CD136 (Antibody to), antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
7381 |
| Gene: |
MST1R |
More about : MST1R |
| Long gene name: |
macrophage stimulating 1 receptor |
| Synonyms gene: |
RON PTK8 |
| Synonyms gene name: |
PTK8 protein tyrosine kinase 8 |
| Synonyms: |
CDw136 CD136 |
| Synonyms name: |
c-met-related tyrosine kinase |
| Locus: |
3p21, 31 |
| Discovery year: |
1993-12-15 |
| GenBank acession: |
X70040 |
| Entrez gene record: |
4486 |
| Pubmed identfication: |
8386824 |
| Classification: |
CD molecules Receptor Tyrosine Kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000156709 |