| known also as: |
Anti-SHEEP ANTI LEPTIN |
| known also as: |
Ovine ANTI LEPTIN |
| known also as: |
Ovinae ANTI LEPTIN |
| known also as: |
LEPTIN |
| Other names: |
Leptin, Obese protein, Obesity factor, homolog of, leptin, leptin, leptin (murine obesity homolog), leptin (obesity homolog, mouse, mouse), obese, obese protein, obesity factor, leptin |
| Gene name: |
LEPTIN |
| Other gene names: |
LEP, LEPD, OB, OB, OBS, OBS, LEP |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Sheep |
| Specificity and cross-reactivity: |
Leptin also acts as a direct stimulator of fatty acid oxidation in the mitochondria of liver and skeletal muscle cells, _x000D__x000D_Regulation of food intake and energy expenditure by leptin is thought to predominantly occur in the hypothalamus of the brain, _x000D__x000D_The expression of leptin in relation to metabolic status is influenced by hormonal and metabolite control: stimulators of leptin include insulin and cortisol, a 16kDa secreted protein hormone encoded by the OB gene, and influences glucose and fat metabolism, and to a lesser extent by stomach endothelium and the placenta, body weight and reproduction and is expressed primarily by white adipocytes, inhibiting the action of the feeding stimulants neuropeptide Y (NPY) and agouti-related peptide (AgRP), or promoting the effects of the appetite regulator ?-melanocyte-stimulating hormone (?-MSH), reduce leptin expression, thiazolidinediones and beta-adrenergic receptor agonists, where leptin binds with high affinity to neuronal leptin receptors (OB-R), which plays a key role in the regulation of metabolism, whilst cAMP, LEPTIN This item recognises leptin |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 5 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
LEPTIN |
| Short name: |
SHEEP ANTI LEPTIN Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ovine antibody to LEPTIN (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8098 |
| Gene: |
OB |
More about : OB |
| Long gene name: |
leptin |
| Synonyms gene: |
OBS |
| Synonyms gene name: |
leptin (murine obesity homolog) leptin (obesity homolog, mouse) |
| Synonyms: |
LEP |
| Locus: |
7q32, 1 |
| Discovery year: |
1993-01-26 |
| Entrez gene record: |
3952 |
| Pubmed identfication: |
1686014 16932309 |
| Havana BLAST/BLAT: |
OTTHUMG00000157564 |