| known also as: |
Anti-RABBIT ANTI GAP43 |
| known also as: |
RABBIT ANTI GAP43 |
| known also as: |
Lapin ANTI GAP43 |
| known also as: |
GAP43 |
| Other names: |
Axonal membrane protein GAP-43, Growth-associated protein 43, N/A, Neuromodulin, axonal membrane protein GAP-43, growth-associated protein 43, neuromodulin, neuromodulin |
| Gene name: |
GAP43 |
| Other gene names: |
GAP43, N/A, N/A, GAP43 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Cat |
| Specificity and cross-reactivity: |
B-50, GAP43 is found tightly associated with neuronal membranes due to palmitoylation, Protein F1 and calmodulin-binding protein P-57) is a protein of approximately 25kD that migrates on SDS-PAGE gels with an apparent size of 40-50kD, The aberrant migration is due to the unusually low abundance of hydrophobic amino acid residues, The solubilised protein binds calmodulin, _x000D__x000D_GAP43 (also known as neuromodulin, a neuronal protein that is expressed at elevated levels during development and also during regenerative axon growth, although this is reduced following protein kinase C phosphorylation of GAP43, pp46, GAP43 This item recognises the protein designated GAP43 |
| Form/Appearance: |
Serum (Serum - liquid) |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB), Immunohistology - Frozen (IHC) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
GAP43 |
| Short name: |
Anti-GAP43 |
| Alternative name: |
antibody to-growth associated protein 43 |
| Alternative to gene target: |
B-50 and PP46, Cell surfaces, GAP43 and IDBG-50973 and ENSG00000172020 and 2596, GAP43 and IDBG-632650 and ENSBTAG00000006451 and 281777, Gap43 and IDBG-160941 and ENSMUSG00000047261 and 14432, calmodulin binding, this GO :0005515 and protein binding and molecular function this GO :0005516 and calmodulin binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007205 and protein kinase C-activating G-protein coupled receptor signaling pathway and biological process this GO :0007399 and nervous system development and biological process this GO :0007411 and axon guidance and biological process this GO :0009611 and response to wounding and biological process this GO :0010001 and glial cell differentiation and biological process this GO :0016198 and axon choice point recognition and biological process this GO :0030054 and cell junction and cellular component this GO :0030424 and axon and cellular component this GO :0031527 and filopodium membrane and cellular component this GO :0032584 and growth cone membrane and cellular component this GO :0040008 and regulation of growth and biological process this GO :0042246 and tissue regeneration and biological process this GO :0045165 and cell fate commitment and biological process this GO :0045202 and synapse and cellular component this GO :0051489 and regulation of filopodium assembly and biological process this GO :0071944 and cell periphery and cellular component, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0005516 : calmodulin binding, this GO :0005516 : calmodulin binding, growth associated protein 43 |
| Identity: |
4140 |
| Gene: |
GAP43 |
More about : GAP43 |
| Long gene name: |
growth associated protein 43 |
| Synonyms: |
B-50 PP46 |
| Synonyms name: |
neuron growth-associated protein 43 neuromodulin nerve growth-related peptide GAP43 axonal membrane protein GAP-43 protein F1 calmodulin-binding protein P-57 neural phosphoprotein B-50 |
| Locus: |
3q13, 31 |
| Discovery year: |
1990-07-10 |
| Entrez gene record: |
2596 |
| Pubmed identfication: |
3272162 8231732 |
| RefSeq identity: |
NM_002045 |
| Havana BLAST/BLAT: |
OTTHUMG00000133758 |