| known also as: |
Anti-RABBIT ANTI Cdk5 (C-TERMINAL) |
| known also as: |
RABBIT ANTI Cdk5 (C-TERMINAL) |
| known also as: |
Lapin ANTI Cdk5 (C-TERMINAL) |
| known also as: |
Cdk5 |
| Other names: |
Cell division protein kinase 5, Cyclin-dependent kinase 5, Serine/threonine-protein kinase PSSALRE, TPKII catalytic subunit, Tau protein kinase II catalytic subunit, cell division protein kinase 5, cyclin-dependent kinase 5, cyclin-dependent kinase 5, protein kinase CDK5 splicing, serine/threonine-protein kinase PSSALRE, tau protein kinase II catalytic subunit, cyclin-dependent kinase 5 isoform 2 |
| Gene name: |
Cdk5 |
| Other gene names: |
CDK5, CDKN5, PSSALRE, TPKII catalytic subunit, CDK5 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
Deregulation of this kinase is neurotoxic and might contribute to the pathogenesis of Alzheimer's disease and other neurodegenerative disorders, Instead, _x000D__x000D_Cdk5 is ubiquitously expressed, a proline-directed serine/threonine protein kinase that unlike most Cdks does not function in cell cycle control, and is not regulated by cyclins, but expression and activity is highest in post mitotic neurones, it requires the association p35 or p39 for its kinase activity, neurotransmitter release and axon guidance, resulting in a master regulator of neuronal functions, where p35 and p39 are highly expressed, with roles in neuronal survival and migration, Cdk5 This item detects human cyclin dependent kinase 5 (Cdk5) |
| Form/Appearance: |
Serum (Serum - liquid) |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Western Blot (WB), Immunoprecipitation (IP) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
Cdk5 |
| Short name: |
Anti-Cdk5 (C-TERMINAL) |
| Alternative name: |
antibody to-cyclin-dependent kinase 5 (C-TERMINAL) |
| Identity: |
1774 |
| Gene: |
CDK5 |
More about : CDK5 |
| Long gene name: |
cyclin dependent kinase 5 |
| Synonyms: |
PSSALRE |
| Locus: |
7q36, 1 |
| Discovery year: |
1993-07-28 |
| GenBank acession: |
X66364 |
| Entrez gene record: |
1020 |
| Pubmed identfication: |
8275715 1639063 |
| Classification: |
Cyclin dependent kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000158414 |