| known also as: |
Anti-RABBIT ANTI TYROSINE HYDROXYLASE (pSer19) |
| known also as: |
RABBIT ANTI TYROSINE HYDROXYLASE (pSer19) |
| known also as: |
Lapin ANTI TYROSINE HYDROXYLASE (pSer19) |
| known also as: |
TYROSINE HYDROXYLASE |
| Other names: |
Tyrosine 3-hydroxylase, Tyrosine 3-monooxygenase, dystonia 14, tyrosine 3-hydroxylase, tyrosine 3-monooxygenase, tyrosine hydroxylase, tyrosine 3-monooxygenase isoform b |
| Other gene names: |
DYT14, DYT5b, TH, TH, TYH, TYH, TH |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Specificity and cross-reactivity: |
Phosphorylation at serine 40 results in an increase in hydroxylase activity, The enzyme exists as a tetramer, _x000D__x000D_Phosphorylation of TH has been shown to occur at several serine residues, _x000D__x000D_Tyrosine hydroxylase (TH) catalyzes the rate-limiting step in the biosynthetic pathway of the catecholamines dopamine (DA), _x000D__x000D_Tyrosine hydroxylase is regularly used as a marker for dopaminergic neurons, and epinephrine, and phosphorylation at serine 19 is reported to promote phosphorylation of the serine 40 residue, norepinephrine, when phosphorylated at serine 19, which is particularly relevant for research into Parkinson's disease, with each subunit composed of an N-terminal regulatory domain and a C-terminal catalytic domain, TYROSINE HYDROXYLASE This item is specific for Tyrosine Hydroxylase |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Storage and shipping: |
Shelf Life: 12 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Immunofluorescence (IF), Western Blot (WB), Immunohistology - Frozen (IHC) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
TYROSINE HYDROXYLASE (pSer19) |
| Short name: |
Anti-TYROSINE HYDROXYLASE (pSer19) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
antibody to-TYROSINE HYDROXYLASE (pSer19) (Antibody to) |
| Alternative technique: |
antibodies |