| known also as: |
Anti-RABBIT ANTI HUMAN SDF-1 ALPHA |
| known also as: |
RABBIT ANTI HUMAN SDF-1 ALPHA |
| known also as: |
Lapin ANTI Homo sapiens SDF-1 ALPHA |
| known also as: |
SDF-1 ALPHA |
| Other names: |
C-X-C motif chemokine 12, IRH, Intercrine reduced in hepatomas, Pre-B cell growth-stimulating factor, Stromal cell-derived factor 1, chemokine (C-X-C motif) ligand 12, hIRH, intercrine reduced in hepatomas, pre-B cell growth-stimulating factor, stromal cell-derived factor 1, stromal cell-derived factor 1 isoform beta |
| Gene name: |
SDF-1 ALPHA |
| Other gene names: |
CXCL12, IRH, IRH, PBSF, PBSF, SCYB12, SDF-1, SDF1, SDF1, SDF1A, SDF1A, SDF1B, SDF1B, TLSF, TPAR1, hIRH, hSDF-1, CXCL12 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
By competitively binding to CXCR4, SDF-1 acts as an inhibitor for the CXCR4-mediated entry of HIV-1 virus into target T-cells, SDF-1 alpha and SDF-1 beta, The two isoforms, _x000D__x000D_SDF-1 binds with high-affinity to the G protein-coupled receptor CXCR4 (fusin) and acts as a chemoattractant for T and B lymphocytes, a 68 amino acid stromal cell derived CXC chemokine, and is a vital factor in haematopoiesis and angiogenesis, and the SDF-1-CXCR4 interaction is important for the regulation of trafficking of normal and malignant stem cells, except for an additional four residues in the C-terminal region of the beta isoform, monocytes and migratory neurons, otherwise known as CXCL12a, share an identical amino acid sequence, which arises from alternative splicing of the SDF-1 gene, SDF-1 ALPHA This item recognises human SDF-1 alpha |
| Form/Appearance: |
Purified (Purified IgG - lyophilised) |
| Concentration: |
0 mg/ml after reconstitution, IgG concentration 1 |
| Storage and shipping: |
After reconstitution For optimal long term storage, Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 12 months from date of reconstitution, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, productone should be kept at -20 degrees Celsius, productone should be stored undiluted, Prior to reconstitution store at +Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Immunohistology - Paraffin (IHC), Western Blot (WB), Functional Assay (FA) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
SDF-1 ALPHA |
| Short name: |
Anti-HUMAN SDF-1 ALPHA Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens SDF-1 a (Antibody to), antibody to-H |
| Alternative technique: |
antibodies |