| known also as: |
Anti-RABBIT ANTI HUMAN ONCOSTATIN M |
| known also as: |
RABBIT ANTI HUMAN ONCOSTATIN M |
| known also as: |
Lapin ANTI Homo sapiens ONCOSTATIN M |
| known also as: |
ONCOSTATIN M |
| Other names: |
N/A, Oncostatin-M, oncostatin M, oncostatin-M, oncostatin-M preproprotein |
| Other gene names: |
N/A, OSM, OSM, OSM |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
OSM signals through binding with low affinity to the gp130 protein present in two cell surface receptors: type I consisting of gp130 and LIFR (leucocyte inhibitory factor receptor) which also acts as a receptor for LIF, _x000D_ _x000D_OSM was identified by the ability to inhibit the replication of various human tumour cell lines, a 209 amino acid pleiotropic cytokine, and to induce the release of certain cytokines by endothelial cells, and type II consisting of gp130 and OSMR, but has also been shown to exert a stimulatory effect on fibroblasts, originally isolated from PMA (phorbol 12-myristate 13-acetate) treated U937 leukaemia cells and mitogen-activated T lymphocytes, smooth muscle cells and Kaposi's sarcoma cells, which mediates OSM specific activities, ONCOSTATIN M This item is specific for human Oncostatin M (OSM) |
| Form/Appearance: |
Purified (Purified IgG - lyophilised) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
After reconstitution For optimal long term storage, Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 12 months from date of reconstitution, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, productone should be kept at -20 degrees Celsius, productone should be stored undiluted, Prior to reconstitution store at +Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Immunohistology - Paraffin (IHC), Western Blot (WB), Functional Assay (FA) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
ONCOSTATIN M |
| Short name: |
Anti-HUMAN ONCOSTATIN M Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens ONCOSTATIN M (Antibody to), antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
8506 |
| Gene: |
OSM |
More about : OSM |
| Long gene name: |
oncostatin M |
| Synonyms: |
MGC20461 |
| Locus: |
22q12, 2 |
| Discovery year: |
1992-07-09 |
| GenBank acession: |
AF129855 |
| Entrez gene record: |
5008 |
| Pubmed identfication: |
1717982 |
| RefSeq identity: |
NM_020530 |
| Classification: |
Interleukin 6 cytokine family |
| Havana BLAST/BLAT: |
OTTHUMG00000150913 |