| known also as: |
Anti-RABBIT ANTI HUMAN MIP-3 BETA |
| known also as: |
RABBIT ANTI HUMAN MIP-3 BETA |
| known also as: |
Lapin ANTI Homo sapiens MIP-3 BETA |
| known also as: |
MIP-3 BETA |
| Other names: |
Beta-chemokine exodus-3, C-C motif chemokine 19, C-C motif chemokine 19, CC chemokine ligand 19, CK beta-11, CK beta-11, EBI1 ligand chemokine, EBI1 ligand chemokine, EBI1-ligand chemokine, ELC, Epstein-Barr virus-induced molecule 1 ligand chemokine, MIP-3-beta, MIP-3-beta, Macrophage inflammatory protein 3 beta, Small-inducible cytokine A19, beta chemokine exodus-3, beta-chemokine exodus-3, chemokine (C-C motif) ligand 19, epstein-Barr virus-induced molecule 1 ligand chemokine, exodus-3, macrophage inflammatory protein 3 beta, macrophage inflammatory protein 3-beta, member 19, small inducible cytokine subfamily A (Cys-Cys), small-inducible cytokine A19, C-C motif chemokine 19 |
| Gene name: |
MIP-3 BETA |
| Other gene names: |
CCL19, CKb11, EBI1 ligand chemokine, ELC, ELC, ELC, MIP-3-beta, MIP-3b, MIP3B, MIP3B, SCYA19, SCYA19, CCL19 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
(Macrophage Inflammatory Protein 3 beta), A correlation between the response to MIP-3 beta and the level of CCR7 expression and has been revealed in the maturation of dendritic cells (DCs), NK cells and myeloid progenitor cells, _x000D__x000D_MIP-3 beta acts as a chemoattractant for T and B lymphocytes, a 77 amino acid CC chemokine expressed at high levels in the thymus and lymph nodes and to a lesser extent in the spleen, a G-protein coupled receptor known to be up-regulated by Epstein-Barr virus infected B cells and herpesvirus infected T cells, and hence T cell recruitment, and increased levels of both MIP-3 beta and CCR7 expression have been shown in bronchoalveolar lavage fluid (BALF) and BALF cells from patients with the granulomatous disorder sarcoidosis, associated predominantly with CD4+ T lymphocyte alveolitis, dendritic cells, kidney, lungs, otherwise known as CCL19, small intestine and stomach, through specific binding to CCR7, MIP-3 BETA This item is specific for human MIP-3 beta |
| Form/Appearance: |
Purified (Purified IgG - lyophilised) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
After reconstitution For optimal long term storage, Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 12 months from date of reconstitution, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, productone should be kept at -20 degrees Celsius, productone should be stored undiluted, Prior to reconstitution store at +Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Western Blot (WB), Functional Assay (FA) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
MIP-3 BETA |
| Short name: |
Anti-HUMAN MIP-3 BETA |
| Alternative name: |
sapiens MIP-3 b, antibody to-H |
| Identity: |
10622 |
| Gene: |
CCL23 |
More about : CCL23 |
| Long gene name: |
C-C motif chemokine ligand 23 |
| Synonyms gene: |
SCYA23 |
| Synonyms gene name: |
member 23 chemokine (C-C motif) ligand 23 , small inducible cytokine subfamily A (Cys-Cys) |
| Synonyms: |
Ckb-8 MPIF-1 MIP-3 CKb8 |
| Locus: |
17q12 |
| Discovery year: |
1997-11-14 |
| GenBank acession: |
U58913 |
| Entrez gene record: |
6368 |
| Pubmed identfication: |
9104803 10409433 |
| RefSeq identity: |
NM_005064 NM_145898 |
| Classification: |
Endogenous ligands Chemokine ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000188409 |