| known also as: |
Anti-RABBIT ANTI HUMAN MCP-2 |
| known also as: |
RABBIT ANTI HUMAN MCP-2 |
| known also as: |
Lapin ANTI Homo sapiens MCP-2 |
| known also as: |
MCP-2 |
| Other names: |
C-C motif chemokine 8, C-C motif chemokine 8, HC14, MCP-2, Monocyte chemoattractant protein 2, Monocyte chemotactic protein 2, Small-inducible cytokine A8, chemokine (C-C motif) ligand 8, member 8 (monocyte chemotactic protein 2), monocyte chemoattractant protein 2, monocyte chemotactic protein 2, small inducible cytokine subfamily A (Cys-Cys), small-inducible cytokine A8, C-C motif chemokine 8 |
| Gene name: |
MCP-2 |
| Other gene names: |
CCL8, HC14, MCP-2, MCP-2, MCP2, MCP2, SCYA10, SCYA10, SCYA8, SCYA8, CCL8 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
MCP-2 (6-76), Proteolytic cleavage of MCP-2 into the NH2-terminally truncated form, _x000D__x000D_MCP-2 acts as a chemoattractant for monocytes, a 76 amino acid CC chemokine originally isolated from the human osteosarcoma cell line MG-63, and also CCR1 and CCR3, chemokine (C-C motif) receptor 2 (CCR2), due to its ability to bind to the common MCP receptor, eosinophils and basophils, forming a functional C-C chemokine inhibitor, lymphocytes, otherwise known as CCL8, results in the loss of chemotactic activity, which is expressed at highest levels in peripheral blood cells and the small intestine, which may be important during inflammatory responses, MCP-2 This item is specific for human MCP-2 (Monocyte Chemoattractant Protein 2) |
| Form/Appearance: |
Purified (Purified IgG - lyophilised) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
After reconstitution For optimal long term storage, Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 12 months from date of reconstitution, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, productone should be kept at -20 degrees Celsius, productone should be stored undiluted, Prior to reconstitution store at +Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Western Blot (WB), Functional Assay (FA) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
MCP-2 |
| Short name: |
Anti-HUMAN MCP-2 |
| Alternative name: |
sapiens MCP-2, antibody to-H |
| Identity: |
10635 |
| Gene: |
CCL8 |
More about : CCL8 |
| Long gene name: |
C-C motif chemokine ligand 8 |
| Synonyms gene: |
SCYA8 |
| Synonyms gene name: |
member 8 (monocyte chemotactic protein 2) chemokine (C-C motif) ligand 8 , small inducible cytokine subfamily A (Cys-Cys) |
| Synonyms: |
MCP-2 HC14 |
| Locus: |
17q12 |
| Discovery year: |
1996-11-14 |
| GenBank acession: |
X99886 |
| Entrez gene record: |
6355 |
| Pubmed identfication: |
9119400 |
| RefSeq identity: |
NM_005623 |
| Classification: |
Endogenous ligands Chemokine ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000132883 |