| known also as: |
Anti-RABBIT ANTI HUMAN MCP-1 |
| known also as: |
RABBIT ANTI HUMAN MCP-1 |
| known also as: |
Lapin ANTI Homo sapiens MCP-1 |
| known also as: |
MCP-1 |
| Other names: |
C-C motif chemokine 2, C-C motif chemokine 2, HC11, MCAF, MCP-1, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, Monocyte chemotactic protein 1, Monocyte secretory protein JE, Small-inducible cytokine A2, chemokine (C-C motif) ligand 2, homologous to mouse Sig-je), member 2, monocyte chemoattractant protein 1, monocyte chemoattractant protein-1, monocyte chemotactic and activating factor, monocyte chemotactic protein 1, monocyte secretory protein JE, small inducible cytokine A2 (monocyte chemotactic protein 1, small inducible cytokine subfamily A (Cys-Cys), small-inducible cytokine A2, C-C motif chemokine 2 |
| Gene name: |
MCP-1 |
| Other gene names: |
CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCAF, MCP-1, MCP-1, MCP1, MCP1, SCYA2, SCYA2, SMC-CF, CCL2 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
CCR2, Increasing studies have also linked MCP-1 with the polarization of activated T cells into the T helper 2 (Th2) subset, _x000D__x000D_The recruitment of mononuclear cells by MCP-1, a 76 amino acid CC chemokine which acts as a chemoattractant for monocytes, activated T cells and NK cells, basophils, has established this chemokine as an important factor in innate immunity, implicated in the pathogenesis of inflammatory diseases such as rheumatoid arthritis, multiple sclerosis, otherwise known as CCL2, revealing a role for MCP-1 in the adaptive immune response, through binding with the seven-transmembrane G protein-coupled receptor, uveitis and bronchial asthma, MCP-1 This item is specific for human MCP-1 (Monocyte Chemoattractant Protein 1) |
| Form/Appearance: |
Purified (Purified IgG - lyophilised) |
| Concentration: |
0 mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Following reconstitution For optimal long term storage, Shelf Life: 12 months from date of reconstitution, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, productone should be kept at -20 degrees Celsius, productone should be stored undiluted, Prior to reconstitution store at +Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Immunohistology - Paraffin (IHC), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
MCP-1 |
| Short name: |
Anti-HUMAN MCP-1 |
| Alternative name: |
sapiens MCP-1, antibody to-H |
| Identity: |
10618 |
| Gene: |
CCL2 |
More about : CCL2 |
| Long gene name: |
C-C motif chemokine ligand 2 |
| Synonyms gene: |
SCYA2 |
| Synonyms gene name: |
homologous to mouse Sig-je) chemokine (C-C motif) ligand 2 , small inducible cytokine A2 (monocyte chemotactic protein 1 |
| Synonyms: |
MCP1 MCP-1 MCAF SMC-CF GDCF-2 HC11 MGC9434 |
| Synonyms name: |
homologous to mouse Sig-je monocyte chemoattractant protein-1 monocyte chemotactic and activating factor monocyte secretory protein JE small inducible cytokine subfamily A (Cys-Cys), member 2 , monocyte chemotactic protein 1 |
| Locus: |
17q12 |
| Discovery year: |
1990-07-05 |
| GenBank acession: |
BC009716 |
| Entrez gene record: |
6347 |
| Pubmed identfication: |
2004761 |
| RefSeq identity: |
NM_002982 |
| Classification: |
Endogenous ligands Chemokine ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000132887 |