| known also as: |
Anti-RABBIT ANTI Smac/DIABLO (C-TERMINAL) |
| known also as: |
RABBIT ANTI Smac/DIABLO (C-TERMINAL) |
| known also as: |
Lapin ANTI Smac/DIABLO (C-TERMINAL) |
| known also as: |
SMAC/DIABLO |
| Other names: |
Diablo homolog, Direct IAP-binding protein with low pI, Second mitochondria-derived activator of caspase, diablo homolog, diablo homolog (Drosophila), direct IAP binding protein with low PI, direct IAP-binding protein with low pI, mitochondrial, mitochondrial, mitochondrial, second mitochondria-derived activator of caspase, diablo homolog |
| Gene name: |
SMAC/DIABLO |
| Other gene names: |
0610041G12Rik, 1700006L01Rik, AU040403, Diablo, Smac, Smac, Smac, Diablo |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Mouse |
| Specificity and cross-reactivity: |
Inhibitors of apoptosis proteins (IAP's) block cell death by caspase inhibition, Smac/DIABLO is expressed in a variety of tissues and has been identified as a negative regulator of XIAP, X-linked inhibitor of apoptosis (XIAP) is a member of the IAP family, SMAC/DIABLO This item recognises the C-terminal region of murine Smac/DIABLO |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
5 mg/ml, IgG concentration 0 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Immunohistology - Paraffin (IHC), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
Smac/DIABLO |
| Short name: |
Anti-Smac/DIABLO (C-TERMINAL) |
| Alternative name: |
IAP-binding mitochondrial protein (C-TERMINAL), antibody to-Smac/diablo |
| Alternative to gene target: |
DIABLO and IDBG-62263 and ENSG00000184047 and 56616, DIABLO and IDBG-632769 and ENSBTAG00000004199 and 493999, Diablo and IDBG-199693 and ENSMUSG00000029433 and 66593, IAP-binding mitochondrial protein, Plasma membranes, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005758 and mitochondrial intermembrane space and cellular component this GO :0005829 and cytosol and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0008625 and extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :0008631 and intrinsic apoptotic signaling pathway in response to oxidative stress and biological process this GO :0008635 and activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c and biological process this GO :0009898 and cytoplasmic side of plasma membrane and cellular component this GO :0035631 and CD40 receptor complex and cellular component this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0051402 and neuron apoptotic process and biological process this GO :0097193 and intrinsic apoptotic signaling pathway and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, diablo |
| Identity: |
21528 |
| Gene: |
DIABLO |
More about : DIABLO |
| Long gene name: |
diablo IAP-binding mitochondrial protein |
| Synonyms gene name: |
IAP-binding mitochondrial protein , diablo |
| Synonyms: |
SMAC DIABLO-S FLJ25049 FLJ10537 DFNA64 |
| Synonyms name: |
second mitochondria-derived activator of caspase |
| Locus: |
12q24, 31 |
| Discovery year: |
2003-10-27 |
| GenBank acession: |
AF262240 |
| Entrez gene record: |
56616 |
| Pubmed identfication: |
12749848 17237824 21722859 |
| RefSeq identity: |
NM_019887 |
| Classification: |
Deafness associated genes |
| Havana BLAST/BLAT: |
OTTHUMG00000157014 |