| known also as: |
Anti-RABBIT ANTI HUMAN CD261 (C-TERMINAL) |
| known also as: |
RABBIT ANTI HUMAN CD261 (C-TERMINAL) |
| known also as: |
Lapin ANTI Homo sapiens CD261 (C-TERMINAL) |
| known also as: |
CD261 |
| Other names: |
Death receptor 4, TNF-related apoptosis-inducing ligand receptor 1, TNF-related apoptosis-inducing ligand receptor 1, TRAIL receptor 1, TRAIL-R1, Tumor necrosis factor receptor superfamily member 10A, cytotoxic TRAIL receptor, death receptor 4, member 10a, tumor necrosis factor receptor superfamily, tumor necrosis factor receptor superfamily member 10A, tumor necrosis factor receptor superfamily member 10a variant 2, tumor necrosis factor receptor superfamily member 10A |
| Gene name: |
CD261 |
| Other gene names: |
APO2, APO2, CD261, DR4, DR4, TNFRSF10A, TRAIL receptor 1, TRAIL-R1, TRAILR-1, TRAILR1, TRAILR1, TNFRSF10A |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
DR4 is a cell surface protein with a death domain that has functional similarities to TNFR1 and CD95, DR4 is expressed in most human tissues, In contrast to CD95, TNFR1 and DR3 it does not use FADD to transmit death signals, The ligand for DR-4 is TRAIL, also known as CD261, and thus DR-4 has also been called TRAIL-RI, CD261 This item recognises the 57kD apoptosis related protein designated DR-4 (death receptor 4) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
5 mg/ml, IgG concentration 0 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Immunohistology - Frozen (IHC), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
CD261 |
| Short name: |
Anti-HUMAN CD261 (C-TERMINAL) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens CD261 (C-TERMINAL) (Antibody to), antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
11904 |
| Gene: |
TNFRSF10A |
More about : TNFRSF10A |
| Long gene name: |
TNF receptor superfamily member 10a |
| Synonyms gene name: |
member 10a , tumor necrosis factor receptor superfamily |
| Synonyms: |
DR4 Apo2 TRAILR-1 CD261 |
| Locus: |
8p21, 3 |
| Discovery year: |
1998-12-04 |
| GenBank acession: |
U90875 |
| Entrez gene record: |
8797 |
| Pubmed identfication: |
9311998 9082980 |
| RefSeq identity: |
NM_003844 |
| Classification: |
CD molecules Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000097843 |