| known also as: |
Anti-RABBIT ANTI HUMAN RAD52 |
| known also as: |
RABBIT ANTI HUMAN RAD52 |
| known also as: |
Lapin ANTI Homo sapiens RAD52 |
| known also as: |
RAD52 |
| Other names: |
DNA repair protein RAD52 homolog, DNA repair protein RAD52 homolog, N/A, RAD52 homolog (S, cerevisiae), recombination protein RAD52, rhabdomyosarcoma antigen MU-RMS-40, 23, DNA repair protein RAD52 homolog |
| Gene name: |
RAD52 |
| Other gene names: |
N/A, N/A, RAD52, RAD52 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
DSBs can be generated through exposure to ionizing radiation or by endogenous cellular reactions, First, In addition, Rad52 and RPA form a co-complex on ssDNA, Rad52 has ssDNA binding and annealing activities, The level rises steadily through S phase reaching a maximum in G2 phase when homologous repair is also at its highest level, _x000D__x000D_Rad52 functions together with Rad51 and RPA (Replication Protein A), _x000D__x000D_Rad52 is present at low levels during the G1 phase of the cell cycle, a protein which functions in DNA repair through the homologous recombination of DNA double strand breaks (DSBs), and Rad52 acts during the latter stages of recombination after the DSBs are processed into single stranded DNA (ssDNA), particularly ssDNA saturated with RPA, when recombinatorial repair is absent, where Rad52 functions to recruit Rad51, where it has two distinct activities, RAD52 This item detects Rad52 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
RAD52 |
| Short name: |
Anti-HUMAN RAD52 |
| Alternative name: |
sapiens RAD52, antibody to-H |
| Identity: |
9824 |
| Gene: |
RAD52 |
More about : RAD52 |
| Long gene name: |
DNA repair protein , RAD52 homolog |
| Synonyms gene name: |
RAD52 (S, cerevisiae) , cerevisiae) homolog RAD52 homolog (S |
| Locus: |
12p13, 33 |
| Discovery year: |
1995-03-28 |
| Entrez gene record: |
5893 |
| Pubmed identfication: |
7774919 18313388 19506022 24340529 |
| RefSeq identity: |
NM_134424 |
| Havana BLAST/BLAT: |
OTTHUMG00000090361 |