| known also as: |
Anti-RABBIT ANTI HUMAN CD11c |
| known also as: |
RABBIT ANTI HUMAN CD11c |
| known also as: |
Lapin ANTI Homo sapiens CD11c |
| known also as: |
CD11c |
| Other names: |
CD11 antigen-like family member C, CD11 antigen-like family member C, Integrin alpha-X, Leu M5, Leukocyte adhesion glycoprotein p150, Leukocyte adhesion receptor p150, alpha X (antigen CD11C (p150), alpha X (complement component 3 receptor 4 subunit), alpha polypeptide), alpha subunit, alpha subunit, alpha subunit, integrin, integrin, integrin alpha-X, leu M5, leukocyte adhesion glycoprotein p150, leukocyte adhesion receptor p150, leukocyte surface antigen p150, myeloid membrane antigen, p150 95 integrin alpha chain, 95, 95, 95, 95 alpha chain, 95 alpha chain, integrin alpha-X |
| Gene name: |
CD11c |
| Other gene names: |
CD11C, CD11C, ITGAX, SLEB6, ITGAX |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
CD11c combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4), CD11c has a number of functions including phagocytosis, CD11c is 150kD in size, ICAM-1, ICAM-4), In light of this, Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain, _x000D__x000D_CD11c binds a myriad of ligands including cell adhesion molecules (e, also known as integrin alpha X (ITGAX), and cytokine production by macrophages/monocytes, and is expressed predominantly on tissue macrophages and dendritic cells, and matrix proteins such as fibrogen and collagen, as well as induction of T cell proliferation by Langerhans cells, bacterial cell wall components (LPS), cell migration, complement protein (iC3b), CD11c This item detects human CD11c, g |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Immunohistology - Paraffin (IHC) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
CD11c |
| Short name: |
Anti-HUMAN CD11c |
| Alternative name: |
sapiens CD11c, antibody to-H |
| Identity: |
6152 |
| Gene: |
ITGAX |
More about : ITGAX |
| Long gene name: |
integrin subunit alpha X |
| Synonyms gene: |
CD11C |
| Synonyms gene name: |
alpha X (antigen CD11C (p150), alpha X (complement component 3 receptor 4 subunit) , alpha polypeptide) integrin, integrin |
| Synonyms: |
CD11c |
| Synonyms name: |
complement component 3 receptor 4 subunit |
| Locus: |
16p11, 2 |
| Discovery year: |
1988-08-15 |
| GenBank acession: |
BC038237 |
| Entrez gene record: |
3687 |
| Pubmed identfication: |
3284962 2303426 |
| RefSeq identity: |
NM_000887 |
| Classification: |
Complement system Integrin alpha subunits CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000132465 |