| known also as: |
Anti-RABBIT ANTI BAG1 (N-TERMINAL) |
| known also as: |
RABBIT ANTI BAG1 (N-TERMINAL) |
| known also as: |
Lapin ANTI BAG1 (N-TERMINAL) |
| known also as: |
BAG1 |
| Other names: |
46-KD, BAG family molecular chaperone regulator 1, BAG family molecular chaperone regulator 1, BCL2-associated athanogene, Bcl-2 associating athanogene-1 protein, Bcl-2-associated athanogene 1, Bcl-2-binding protein, glucocortoid receptor-associated protein RAP46, receptor-associated protein, BAG family molecular chaperone regulator 1 isoform BAG-1S |
| Gene name: |
BAG1 |
| Other gene names: |
BAG-1, BAG-1, BAG1, HAP, HAP, RAP46, BAG1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
BAG1 has also been shown to interact with the kinase Raf1, BAG1 may also promote chemoresistance, It is thought to function as a molecular switch between cell growth and differentiation, _x000D__x000D_BAG1 displays potent neuroprotective activity in vivo against stroke, _x000D__x000D_The <, a 46kD cytosolic and nuclear form (BAG1M), a co-chaperone protein which binds to and regulates the 70kD heat shock proteins (Hsp70/Hsc70), a number of steroid and tyrosine kinase receptors, a predominantly cytosolic form of 36kD (BAG1S), and a predominantly nuclear form 50kD (BAG1L), and anchorage independent cell growth in tumour cells, and cell survival, and could be used for reducing brain injury during cerebral ischemia and neurodegenerative diseases, and the Bcl-2 family of proteins, gene encodes three different isoforms, growth factor independence, /i>, BAG1 This item detects an epitope within the N-terminal (NT) region of Bcl-2 associated athanogene-1 (BAG1), BAG1<, i> |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
BAG1 |
| Short name: |
Anti-BAG1 (N-TERMINAL) |
| Alternative name: |
antibody to-B-cell CLL/lymphoma 2-associated athanogene (N-TERMINAL) |
| Alternative to gene target: |
BAG-1 and HAP and RAP46, BAG1 and IDBG-56882 and ENSG00000107262 and 573, BAG1 and IDBG-635765 and ENSBTAG00000017845 and 613855, Bag1 and IDBG-136600 and ENSMUSG00000028416 and 12017, nuclei, phosphoprotein binding, this GO :0001933 and negative regulation of protein phosphorylation and biological process this GO :0005057 and receptor signaling protein activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0030182 and neuron differentiation and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043525 and positive regulation of neuron apoptotic process and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0051087 and chaperone binding and molecular function this GO :0051219 and phosphoprotein binding and molecular function this GO :0070389 and chaperone cofactor-dependent protein refolding and biological process this GO :0070585 and protein localization to mitochondrion and biological process this GO :2000672 and negative regulation of motor neuron apoptotic process and biological process, this GO :0005057 : receptor signaling protein activity, this GO :0005057 : receptor signaling protein activity and also this GO :0005515 : protein binding and also this GO :0051087 : chaperone binding and also this GO :0051219 : phosphoprotein binding, this GO :0005515 : protein binding, this GO :0051087 : chaperone binding, this GO :0051219 : phosphoprotein binding, 781741, BCL2-associated athanogene |
| Identity: |
937 |
| Gene: |
BAG1 |
More about : BAG1 |
| Long gene name: |
BCL2 associated athanogene 1 |
| Synonyms gene name: |
BCL2 associated athanogene |
| Locus: |
9p13, 3 |
| Discovery year: |
1996-06-19 |
| GenBank acession: |
AF022224 |
| Entrez gene record: |
573 |
| Pubmed identfication: |
7834747 |
| RefSeq identity: |
NM_004323 |
| Classification: |
BCL2 associated athanogene family |
| Havana BLAST/BLAT: |
OTTHUMG00000019766 |