| known also as: |
Anti-RABBIT ANTI HUMAN BACE1 (N-TERMINAL) |
| known also as: |
RABBIT ANTI HUMAN BACE1 (N-TERMINAL) |
| known also as: |
Lapin ANTI Homo sapiens BACE1 (N-TERMINAL) |
| known also as: |
BACE1 |
| Other names: |
APP beta-secretase, ASP2, Asp 2, Aspartyl protease 2, Beta-secretase 1, Beta-site APP cleaving enzyme 1, Beta-site amyloid precursor protein cleaving enzyme 1, Memapsin-2, Membrane-associated aspartic protease 2, asp 2, aspartyl protease 2, beta-secretase 1, beta-secretase 1 precursor variant 1, beta-site APP cleaving enzyme 1, beta-site APP-cleaving enzyme 1, beta-site amyloid beta A4 precursor protein-cleaving enzyme, memapsin-2, membrane-associated aspartic protease 2, transmembrane aspartic proteinase Asp2, beta-secretase 1 isoform F |
| Gene name: |
BACE1 |
| Other gene names: |
ASP2, ASP2, Asp 2, BACE, BACE, BACE1, HSPC104, KIAA1149, BACE1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
Amyloid beta peptide is the major constituent of amyloid plaques in the brains of individuals afflicted with Alzheimer's disease, BACE1 is a member of the peptidase A1 protein family, _x000D__x000D_BACE1 catalyzes the cleavage of beta APP at the extracellular, a 75kD type I integral membrane glycoprotein and aspartic protease, amino-terminal domain leading to the formation of amyloid beta peptide, and is expressed by neurons and astrocytes in the brain, BACE1 This item detects an epitope near the N-terminal region of human b-site amyloid precursor protein (APP)-cleaving enzyme 1 (BACE1) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Immunohistology - Paraffin (IHC) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
BACE1 |
| Short name: |
Anti-HUMAN BACE1 (N-TERMINAL) |
| Alternative name: |
sapiens BACE1 (N-TERMINAL), antibody to-H |
| Identity: |
933 |
| Gene: |
BACE1 |
More about : BACE1 |
| Long gene name: |
beta-secretase 1 |
| Synonyms gene: |
BACE |
| Synonyms gene name: |
beta-site APP-cleaving enzyme beta-site APP-cleaving enzyme 1 |
| Locus: |
11q23, 3 |
| Discovery year: |
1999-10-29 |
| GenBank acession: |
AF190725 |
| Entrez gene record: |
23621 |
| Pubmed identfication: |
10531052 |
| Havana BLAST/BLAT: |
OTTHUMG00000160636 |