| known also as: |
Anti-GOAT ANTI HUMAN TRADD (ISOFORM2) |
| known also as: |
Caprine ANTI HUMAN TRADD (ISOFORM2) |
| known also as: |
Caprinae ANTI Homo sapiens TRADD (ISOFORM2) |
| known also as: |
TRADD |
| Other names: |
TNFR1-associated death domain protein, TNFRSF1A-associated via death domain, TNFRSF1A-associated via death domain, Tumor necrosis factor receptor type 1-associated DEATH domain protein, tumor necrosis factor receptor type 1 associated death domain protein, tumor necrosis factor receptor type 1-associated DEATH domain protein, tumor necrosis factor receptor-1-associated protein, tumor necrosis factor receptor type 1-associated DEATH domain protein |
| Gene name: |
TRADD |
| Other gene names: |
Hs, TNFR1-associated DEATH domain protein, TRADD, 89862, TRADD |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Goat |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
By binding the adaptor protein TRAF2, It mediates programmed cell death signalling and NF-kappa beta activation through interaction with tumour necrosis factor receptor superfamily, TRADD is also involved in the Fas-induced cell death pathway via its interaction with tumour necrosis factor receptor superfamily, TRADD is expressed in most tissues, TRADD reduces the recruitment of inhibitor-of-apoptosis proteins, a 28kDa death domain containing protein, inhibiting TRAF2 mediated apoptosis, member 1A, member-6/FAS and adaptor protein FADD/MORT1, TRADD This item recognises tumour necrosis factor receptor 1-associated death domain protein (TRADD) isoform 2 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
5 mg/ml, IgG concentration 0 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
TRADD (ISOFORM2) |
| Short name: |
GOAT ANTI HUMAN TRADD (ISOFORM2) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens TNFRSF1A-associated via death domain (ISOFORM2) (Antibody to), caprine antibody to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Hs, TRADD and IDBG-36010 and ENSG00000102871 and 8717, TRADD and IDBG-633302 and ENSBTAG00000012642 and 504707, Tradd and IDBG-186918 and ENSMUSG00000031887 and 71609, binding, bridging, bridging and also this GO :0070513 : death domain binding, bridging and molecular function this GO :0070513 and death domain binding and molecular function this GO :0097190 and apoptotic signaling pathway and biological process this GO :0097191 and extrinsic apoptotic signaling pathway and biological process this GO :2001239 and regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, nuclei, this GO :0004871 and signal transducer activity and molecular function this GO :0005164 and tumor necrosis factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0008625 and extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :0019900 and kinase binding and molecular function this GO :0031264 and death-inducing signaling complex and cellular component this GO :0032403 and protein complex binding and molecular function this GO :0033209 and tumor necrosis factor-mediated signaling pathway and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043234 and protein complex and cellular component this GO :0043235 and receptor complex and cellular component this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051291 and protein heterooli this GO merization and biological process this GO :0051798 and positive regulation of hair follicle development and biological process this GO :0060090 and binding, this GO :0004871 : signal transducer activity, this GO :0004871 : signal transducer activity and also this GO :0005164 : tumor necrosis factor receptor binding and also this GO :0005515 : protein binding and also this GO :0019900 : kinase binding and also this GO :0032403 : protein complex binding and also this GO :0042802 : identical protein binding and also this GO :0060090 : binding, this GO :0005164 : tumor necrosis factor receptor binding, this GO :0005515 : protein binding, this GO :0019900 : kinase binding, this GO :0032403 : protein complex binding, this GO :0042802 : identical protein binding, this GO :0060090 : binding, this GO :0070513 : death domain binding, 89862, TNFRSF1A-associated via death domain |
| Identity: |
12030 |
| Gene: |
TRADD |
More about : TRADD |
| Long gene name: |
TNFRSF1A associated via death domain |
| Synonyms gene name: |
TNFRSF1A-associated via death domain |
| Synonyms: |
Hs, 89862 |
| Locus: |
16q22, 1 |
| Discovery year: |
1999-05-07 |
| GenBank acession: |
L41690 |
| Entrez gene record: |
8717 |
| Pubmed identfication: |
7758105 22333735 |
| Havana BLAST/BLAT: |
OTTHUMG00000137519 |