| known also as: |
Anti-RABBIT ANTI BECLIN-1 (N-TERMINAL) |
| known also as: |
RABBIT ANTI BECLIN-1 (N-TERMINAL) |
| known also as: |
Lapin ANTI BECLIN-1 (N-TERMINAL) |
| known also as: |
BECLIN-1 |
| Other names: |
Beclin-1, Coiled-coil myosin-like BCL2-interacting protein, Protein GT197, autophagy related, beclin 1, beclin 1 (coiled-coil, beclin-1, coiled-coil myosin-like BCL2-interacting protein, myosin-like BCL2-interacting protein), beclin-1 |
| Other gene names: |
Becn1, N/A, N/A, Becn1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
An increasing number of studies have revealed an interaction between proteins which induce autophagy and those involved in apoptosis and in some instances apoptosis may be dependant upon or delayed by autophagy, Studies have identified Beclin-1 as a Bcl-2 interacting mammalian gene which not only mediates autophagy, _x000D__x000D_The ability of cells to undergo bulk degradation of endogenous proteins through an autophagosomic-lysosomal pathway, a 52kDa coiled-coil protein which shares structural homology with the yeast autophagy gene apg6/vps30, and may also play a role in defense against viral infection, being expressed at reduced levels in human breast carcinoma, but also functions as a tumour suppressor, is important in the control of cell growth and development, termed autophagy or Type II cell death, BECLIN-1 This item recognises an epitope within the N-terminal region of Beclin-1 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Flow Cytometry (FACS), Western Blot (WB), Immunohistology - Paraffin (IHC) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
BECLIN-1 |
| Short name: |
Anti-BECLIN-1 (N-TERMINAL) |
| Alternative name: |
antibody to-BECLIN-1 (N-TERMINAL) |