| known also as: |
Anti-GOAT ANTI HUMAN LNK (N-TERMINAL) |
| known also as: |
Caprine ANTI HUMAN LNK (N-TERMINAL) |
| known also as: |
Caprinae ANTI Homo sapiens LNK (N-TERMINAL) |
| known also as: |
LNK |
| Other names: |
Lymphocyte adapter protein, Lymphocyte-specific adapter protein Lnk, SH2B adapter protein 3, SH2B adapter protein 3, SH2B adaptor protein 3, Signal transduction protein Lnk, lymphocyte-specific adapter protein Lnk, signal transduction protein Lnk, SH2B adapter protein 3 |
| Gene name: |
LNK |
| Other gene names: |
IDDM20, LNK, LNK, SH2B3, SH2B3 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Goat |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
The role of LNK as a negative regulator, _x000D__x000D_LNK mRNA is preferentially expressed in lymph node and spleen lymphocytes and the expression of LNK in vascular endothelial cells (ECs), an SH2-containing adaptor protein, and negative regulation of Thrombopoietin-mediated cell proliferation and endomitosis in hematopoietic cell lines, and plays an essential role in B cell lymphopoiesis, includes the down regulation of the pro-inflammatory molecules VCAM-1 and E-selectin induced by TNF?, increases in response to TNF?, modulation of P13-kinase and MAPK ERK1/2 activity, which regulates cytokine receptor-mediated and growth factor pathways, <, LNK This item recognises an epitope within the N-terminal region (NT) of lymphocyte adaptor protein (LNK), _x000D_, br / |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
IgG concentration 500ug/1000ul |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
LNK |
| Short name: |
GOAT ANTI HUMAN LNK (N-TERMINAL) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens LNK (N-TERMINAL) (Antibody to), caprine antibody to H |
| Alternative technique: |
antibodies |
| Identity: |
29605 |
| Gene: |
SH2B3 |
More about : SH2B3 |
| Long gene name: |
SH2B adaptor protein 3 |
| Synonyms: |
LNK IDDM20 |
| Synonyms name: |
lymphocyte adaptor protein |
| Locus: |
12q24, 12 |
| Discovery year: |
2006-07-04 |
| GenBank acession: |
AF055581 |
| Entrez gene record: |
10019 |
| Pubmed identfication: |
10799879 |
| RefSeq identity: |
NM_005475 |
| Classification: |
Pleckstrin homology domain containing SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000169550 |
| Locus Specific Databases: |
LRG_621 |