| Long name: |
CLNS1A Primary Polyclonal Antibody |
| Also known as: |
CLNS1A PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
CLNS1A |
| Specificity: |
This is a highly specific antibody against CLNS1A |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CLNS1A/pICln |
| Gene ID number: |
1207 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
JBP1), PRMT5 binds the Sm proteins via their arginine- and glycine-rich (RG) domains, The gene encoding human pICln maps to chromosome 11q14, This process is mediated by the survival of motor neuron (SMN) protein, a complex comprised of the type II methyltransferase PRMT5 (also designated Jak-binding protein 1, and is enhanced by modification of specific arginine residues in the Sm proteins to symmetrical dimethylarginines (sDMAs), and may play a role as a swelling-activated anion channel or a channel regulator in addition to its function in the methylosome, and two novel factors, pICln, pICln also acts as an inhibitor of SnRNP assembly by preventing specific interactions between Sm proteins required for the formation of the Sm core, pICln is a highly conserved, sDMA modification of Sm proteins is catalyzed by the methylosome, ubiquitously expressed protein that localizes primarily to the cytoplasm, while pICln binds the Sm domains, 1, The formation of the spliceosome includes the assembly of Sm proteins in an ordered manner onto snRNAs |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CLNS 1A, CLNS1B, Chloride channel, Chloride channel nucleotide sensitive 1A, Chloride channel regulatory protein, Chloride conductance regulatory protein ICln, Chloride ion current inducer protein, ClCI, Clns1a, ICLN_HUMAN, ICln, ICln, Methylosome subunit pICln, Reticulocyte pICln, nucleotide sensitive 1A |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CLNS1A |
| Short name: |
CLNS1A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CLNS1A (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2080 |
| Gene: |
CLNS1A |
More about : CLNS1A |
| Long gene name: |
chloride nucleotide-sensitive channel 1A |
| Synonyms gene: |
CLCI |
| Synonyms gene name: |
1A , chloride channel, nucleotide-sensitive |
| Synonyms: |
ICln |
| Synonyms name: |
methylosome subunit pICln |
| Locus: |
11q14, 1 |
| Discovery year: |
1997-10-16 |
| GenBank acession: |
U17899 |
| Entrez gene record: |
1207 |
| Pubmed identfication: |
7887970 8975725 |
| RefSeq identity: |
NM_001293 |
| Havana BLAST/BLAT: |
OTTHUMG00000165143 |